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Literature summary extracted from

  • Chauncey, T.R.; Westley, J.
    The catalytic mechanism of yeast thiosulfate reductase (1983), J. Biol. Chem., 258, 15037-15045.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.1.3 benzene sulfinate competitive with both substrates Saccharomyces cerevisiae
2.8.1.3 sulfate non-competitive inhibition when glutathione is the varied substrate Saccharomyces cerevisiae
2.8.1.3 sulfite competitive inhibition when glutathione is the varied substrate Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.1.3 0.24
-
Benzenethiosulfonate pH 8.1, 37°C Saccharomyces cerevisiae
2.8.1.3 0.89
-
glutathione pH 8.1, 37°C, with benzenethiosulfonate as the other substrate Saccharomyces cerevisiae
2.8.1.3 2.9
-
thiosulfate pH 8.1, 37°C Saccharomyces cerevisiae
2.8.1.3 4
-
glutathione pH 8.1, 37°C, with thiosulfate as the other substrate Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.1.3 thiosulfate + glutathione Saccharomyces cerevisiae
-
sulfite + glutathione disulfide + sulfide
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.8.1.3 Saccharomyces cerevisiae
-
Red Star brand
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.1.3 benzenethiosulfonate + glutathione rapid equilibrium-ordered mechanism with glutathione as leading substrate Saccharomyces cerevisiae additional information glutathione persulfide as an immediate product ?
2.8.1.3 thiosulfate + glutathione
-
Saccharomyces cerevisiae sulfite + glutathione disulfide + sulfide
-
?
2.8.1.3 thiosulfate + glutathione
-
Saccharomyces cerevisiae sulfite + glutathione disulfide + sulfide the primary product is glutathione hydrodisulfide, which reacts with glutathione to give oxidized glutathione and sulfide ?