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Literature summary extracted from

  • Bouhss, A.; Mengin-Lecreulx, D.; Le Beller, D.; Van Heijenoort, J.
    Topological analysis of the MraY protein catalysing the first membrane step of peptidoglycan synthesis (1999), Mol. Microbiol., 34, 576-585.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.8.13 Staphylococcus aureus MraY is functional in Escherichia coli Staphylococcus aureus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.13 cytoplasm
-
Staphylococcus aureus 5737
-
2.7.8.13 cytoplasm
-
Escherichia coli 5737
-
2.7.8.13 membrane
-
Staphylococcus aureus 16020
-
2.7.8.13 membrane
-
Escherichia coli 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.13 UDP-NAc-muramoyl-pentapeptide + acceptor Staphylococcus aureus biosynthesis of peptidoglycan, first lipid intermediate UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r
2.7.8.13 UDP-NAc-muramoyl-pentapeptide + acceptor Escherichia coli biosynthesis of peptidoglycan, first lipid intermediate UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.13 Escherichia coli
-
-
-
2.7.8.13 Staphylococcus aureus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.13 additional information catalyzes an exchange reaction between UMP and UDP-MurNAc-pentapeptide in the absence of undecaprenyl phosphate Staphylococcus aureus ?
-
?
2.7.8.13 additional information catalyzes an exchange reaction between UMP and UDP-MurNAc-pentapeptide in the absence of undecaprenyl phosphate Escherichia coli ?
-
?
2.7.8.13 UDP-NAc-muramoyl-pentapeptide + acceptor
-
Staphylococcus aureus UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r
2.7.8.13 UDP-NAc-muramoyl-pentapeptide + acceptor
-
Escherichia coli UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r
2.7.8.13 UDP-NAc-muramoyl-pentapeptide + acceptor biosynthesis of peptidoglycan, first lipid intermediate Staphylococcus aureus UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r
2.7.8.13 UDP-NAc-muramoyl-pentapeptide + acceptor biosynthesis of peptidoglycan, first lipid intermediate Escherichia coli UMP + acceptor-phospho-NAc-muramoyl-pentapeptide
-
r

Synonyms

EC Number Synonyms Comment Organism
2.7.8.13 MraY protein
-
Staphylococcus aureus
2.7.8.13 MraY protein
-
Escherichia coli
2.7.8.13 MraY transferase
-
Staphylococcus aureus
2.7.8.13 MraY transferase
-
Escherichia coli