EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.6.1.81 | additional information | arginine induces the enzyme, enzyme induction by arginine is diminished by addition of succinate, L-glutamate or NH4+ in the growth medium, overview | Burkholderia cepacia |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.6.1.81 | aminooxoacetic acid | - |
Burkholderia cepacia | |
2.6.1.81 | additional information | arginine induces the enzyme, enzyme induction by arginine is diminished by addition of succinate, L-glutamate or NH4+ in the growth medium, overview | Burkholderia cepacia |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.6.1.11 | 1.25 | - |
N2-succinyl-L ornithine | - |
Burkholderia cepacia | |
2.6.1.11 | 6.3 | - |
N2-Acetyl-L-ornithine | - |
Burkholderia cepacia | |
2.6.1.11 | 100 | - |
L-ornithine | - |
Burkholderia cepacia | |
2.6.1.81 | 1.25 | - |
N2-succinyl-L-ornithine | pH 8.5, 37°C, cell extract | Burkholderia cepacia | |
3.5.1.96 | 0.2 | - |
N-succinyl-L-glutamate | pH 8.5, 37°C | Burkholderia cepacia | |
3.5.3.23 | 1.5 | - |
N2-succinyl-L-arginine | pH 7.8 | Burkholderia cepacia |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.5.1.96 | Co2+ | stimulation | Burkholderia cepacia |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.71 | N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O | Burkholderia cepacia | fourth enzyme of arginine succinyltransferase pathway | N-succinyl-L-glutamate + NADH + H+ | - |
? | |
2.6.1.11 | N2-acetyl-L-ornithine + 2-oxoglutarate | Burkholderia cepacia | arginine degradation, arginine-inducible catabolic enzyme | N-acetyl-L-glutamate-gamma-semialdehyde + L-glutamate | - |
? | |
2.6.1.11 | N2-acetyl-L-ornithine + 2-oxoglutarate | Burkholderia cepacia NCTC 10743 | arginine degradation, arginine-inducible catabolic enzyme | N-acetyl-L-glutamate-gamma-semialdehyde + L-glutamate | - |
? | |
2.6.1.81 | N2-succinyl-L-ornithine + 2-oxoglutarate | Burkholderia cepacia | step in metabolic conversion of L-arginine into L-glutamate, pathway overview | N-succinyl-L-glutamate 5-semialdehyde + L-glutamate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.71 | Burkholderia cepacia | - |
NCTC 10743 | - |
2.6.1.11 | Burkholderia cepacia | - |
NCTC 10743 | - |
2.6.1.81 | Burkholderia cepacia | - |
- |
- |
2.6.1.81 | Burkholderia cepacia NCTC 10743 | - |
- |
- |
3.5.1.96 | Burkholderia cepacia | - |
- |
- |
3.5.1.96 | Burkholderia cepacia NCTC 10743 | - |
- |
- |
3.5.3.23 | Burkholderia cepacia | - |
- |
- |
3.5.3.23 | Burkholderia cepacia NCTC 10743 | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.6.1.81 | culture condition:arginine-grown cell | - |
Burkholderia cepacia | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.6.1.81 | 0.027 | - |
succinate/ammonium-grown cells, cell extract | Burkholderia cepacia |
2.6.1.81 | 1.07 | - |
arginine-grown cells, induced enzyme, cell extract | Burkholderia cepacia |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.71 | N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O | - |
Burkholderia cepacia | N-succinyl-L-glutamate + NADH + H+ | - |
? | |
1.2.1.71 | N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O | fourth enzyme of arginine succinyltransferase pathway | Burkholderia cepacia | N-succinyl-L-glutamate + NADH + H+ | - |
? | |
1.2.1.71 | N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O | - |
Burkholderia cepacia NCTC 10743 | N-succinyl-L-glutamate + NADH + H+ | - |
? | |
2.6.1.11 | L-ornithine + 2-oxoglutarate | - |
Burkholderia cepacia | ? | - |
? | |
2.6.1.11 | L-ornithine + 2-oxoglutarate | - |
Burkholderia cepacia NCTC 10743 | ? | - |
? | |
2.6.1.11 | N2-acetyl-L-ornithine + 2-oxoglutarate | arginine degradation, arginine-inducible catabolic enzyme | Burkholderia cepacia | N-acetyl-L-glutamate-gamma-semialdehyde + L-glutamate | - |
? | |
2.6.1.11 | N2-acetyl-L-ornithine + 2-oxoglutarate | arginine degradation, arginine-inducible catabolic enzyme | Burkholderia cepacia NCTC 10743 | N-acetyl-L-glutamate-gamma-semialdehyde + L-glutamate | - |
? | |
2.6.1.11 | N2-acetyl-L-ornithine + 2-oxohexanedioic acid | i.e. 2-ketoadipate | Burkholderia cepacia | N-acetyl-L-glutamate 5-semialdehyde + 2-aminohexanedioic acid | - |
? | |
2.6.1.11 | N2-acetyl-L-ornithine + 2-oxohexanedioic acid | i.e. 2-ketoadipate | Burkholderia cepacia NCTC 10743 | N-acetyl-L-glutamate 5-semialdehyde + 2-aminohexanedioic acid | - |
? | |
2.6.1.11 | N2-succinyl-L-ornithine + 2-oxoglutarate | - |
Burkholderia cepacia | N2-succinylglutamate semialdehyde + glutamate | - |
? | |
2.6.1.11 | N2-succinyl-L-ornithine + 2-oxoglutarate | - |
Burkholderia cepacia NCTC 10743 | N2-succinylglutamate semialdehyde + glutamate | - |
? | |
2.6.1.81 | N2-succinyl-L-ornithine + 2-oxoglutarate | - |
Burkholderia cepacia | N-succinyl-L-glutamate 5-semialdehyde + L-glutamate | - |
? | |
2.6.1.81 | N2-succinyl-L-ornithine + 2-oxoglutarate | step in metabolic conversion of L-arginine into L-glutamate, pathway overview | Burkholderia cepacia | N-succinyl-L-glutamate 5-semialdehyde + L-glutamate | - |
? | |
3.5.1.96 | additional information | no substrate: N2-acetylglutamate | Burkholderia cepacia | ? | - |
? | |
3.5.1.96 | N-succinyl-L-glutamate + H2O | - |
Burkholderia cepacia | succinate + L-glutamate | - |
? | |
3.5.3.23 | additional information | no substrate: L-arginine, N2-acetylarginine, N2-glutamylarginine | Burkholderia cepacia | ? | - |
? | |
3.5.3.23 | N2-succinyl-L-arginine + H2O | - |
Burkholderia cepacia | N2-succinyl-L-ornithine + NH3 + CO2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.6.1.81 | succinylornithine aminotransferase | - |
Burkholderia cepacia |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.6.1.11 | 37 | - |
assay at | Burkholderia cepacia |
2.6.1.81 | 37 | - |
assay at | Burkholderia cepacia |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.6.1.11 | 8.2 | - |
N2-acetyl-L-ornithine | Burkholderia cepacia |
2.6.1.11 | 8.6 | - |
N2-succinyl-L-ornithine | Burkholderia cepacia |
2.6.1.81 | 8.6 | - |
- |
Burkholderia cepacia |
3.5.1.96 | 8.5 | - |
- |
Burkholderia cepacia |
3.5.3.23 | 7.8 | - |
- |
Burkholderia cepacia |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.6.1.81 | pyridoxal 5'-phosphate | - |
Burkholderia cepacia |
EC Number | Organism | Comment | Expression |
---|---|---|---|
3.5.1.96 | Burkholderia cepacia | presence of succinate, glutamine, and to a lesser extent glutamate represses expression | down |
3.5.1.96 | Burkholderia cepacia | presence of arginine elicits expression | up |