Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • De Renzo, E.C.
    Chemistry and biochemistry of xanthine oxidase (1956), Adv. Enzymol. Relat. Subj. Biochem., 17, 293-328.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.3.2 2-Amino-4-hydroxy-6-formylpterine
-
 Gallus gallus
1.17.3.2 2-Amino-4-hydroxy-6-formylpterine
-
 Rattus norvegicus
1.17.3.2 8-Hydroxyquinoline-7-sulfonic acid
-
 Gallus gallus
1.17.3.2 8-Hydroxyquinoline-7-sulfonic acid
-
 Rattus norvegicus
1.17.3.2 alloxan
-
 Gallus gallus
1.17.3.2 alloxan
-
 Rattus norvegicus
1.17.3.2 arsenite
-
 Bos taurus
1.17.3.2 arsenite
-
 Rattus norvegicus
1.17.3.2 ascorbic acid
-
 Rattus norvegicus
1.17.3.2 Borate
-
 Gallus gallus
1.17.3.2 Borate
-
 Rattus norvegicus
1.17.3.2 chalcones
-
 Gallus gallus
1.17.3.2 chalcones
-
 Rattus norvegicus
1.17.3.2 copper
-
 Bos taurus
1.17.3.2 cyanide
-
 Bos taurus
1.17.3.2 cyanide
-
 Gallus gallus
1.17.3.2 cyanide
-
 Rattus norvegicus
1.17.3.2 hydroxylamine
-
 Bos taurus
1.17.3.2 hydroxylamine
-
 Gallus gallus
1.17.3.2 hydroxylamine
-
 Rattus norvegicus
1.17.3.2 Imidazotriazines
-
 Gallus gallus
1.17.3.2 Imidazotriazines
-
 Rattus norvegicus
1.17.3.2 isatin
-
 Gallus gallus
1.17.3.2 isatin
-
 Rattus norvegicus
1.17.3.2 ninhydrin
-
 Gallus gallus
1.17.3.2 ninhydrin
-
 Rattus norvegicus
1.17.3.2 p-chloromercuribenzoate
-
 Bos taurus
1.17.3.2 p-chloromercuribenzoate
-
 Gallus gallus
1.17.3.2 p-chloromercuribenzoate
-
 Rattus norvegicus
1.17.3.2 Tetraethylthiuram disulfide
-
 Gallus gallus
1.17.3.2 Tetraethylthiuram disulfide
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.17.3.2 0.0005
-
 NADPH cofactor 2,6-dichlorophenolindophenol Bos taurus
1.17.3.2 0.0475
-
 hypoxanthine cofactor 2,6-dichlorophenolindophenol Bos taurus
1.17.3.2 0.088
-
 xanthine cofactor 2,6-dichlorophenolindophenol Bos taurus
1.17.3.2 20
-
 aldehyde cofactor 2,6-dichlorophenolindophenol Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.17.3.2 Iron iron-molybdenum protein Gallus gallus
1.17.3.2 Iron iron-molybdenum protein Rattus norvegicus
1.17.3.2 Iron iron-molybdenum protein Bos taurus
1.17.3.2 Molybdenum an iron-molybdenum protein Gallus gallus
1.17.3.2 Molybdenum an iron-molybdenum protein Rattus norvegicus
1.17.3.2 Molybdenum an iron-molybdenum protein Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.17.3.2 additional information
-
-
 Gallus gallus
1.17.3.2 additional information
-
-
 Rattus norvegicus
1.17.3.2 additional information
-
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Bos taurus
-
-
-
1.17.3.2 Gallus gallus
-
-
-
1.17.3.2 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.17.3.2 additional information
-
 Gallus gallus
1.17.3.2 additional information
-
 Rattus norvegicus
1.17.3.2 additional information
-
 Bos taurus
1.17.3.2 proteolytic modification
-
 Gallus gallus
1.17.3.2 proteolytic modification
-
 Rattus norvegicus
1.17.3.2 proteolytic modification
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 milk
-
 Rattus norvegicus
-
1.17.3.2 milk
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 aldehyde + indophenol
-
 Bos taurus ?
-
 r
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
 Gallus gallus urate + 2 H2O2
-
 ?
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
 Rattus norvegicus urate + 2 H2O2
-
 ?
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
 Bos taurus urate + 2 H2O2
-
 ?
1.17.3.2 NADPH + indophenol
-
 Bos taurus ?
-
 r
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Gallus gallus uric acid + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Rattus norvegicus uric acid + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Bos taurus uric acid + H2O2
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.17.3.2 1.28
-
 NADPH cosubstrate cytochrome c Bos taurus
1.17.3.2 2.57
-
 NADPH cosubstrate indophenol Bos taurus
1.17.3.2 4.35
-
 hypoxanthine cofactor 2,6-dichlorophenolindophenol Bos taurus
1.17.3.2 4.92
-
 xanthine (+ O2) Bos taurus
1.17.3.2 5.25
-
 xanthine cofactor 2,6-dichlorophenolindophenol Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.3.2 FAD flavoprotein Gallus gallus
1.17.3.2 FAD flavoprotein Rattus norvegicus
1.17.3.2 FAD flavoprotein Bos taurus