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Literature summary extracted from

  • Hayden, T.J.; Ryan, J.P.; Duke, E.J.
    Comparative aspects of xanthine-oxygen oxidoreductase systems (1973), Biochem. Soc. Trans., 1, 247-250.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.3.2 Azaguanine
-
 Locusta sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.17.3.2 additional information
-
 additional information
-
 Drosophila melanogaster
1.17.3.2 additional information
-
 additional information
-
 Mus musculus
1.17.3.2 additional information
-
 additional information
-
 Locusta sp.
1.17.3.2 0.00143
-
 2-Amino-4-hydroxypteridine + methylene blue Locusta sp.
1.17.3.2 0.0067
-
 2-Amino-4-hydroxypteridine + methylene blue Drosophila melanogaster
1.17.3.2 0.024
-
 xanthine kidney enzyme Gallus gallus
1.17.3.2 0.025
-
 xanthine
-
 Mus musculus
1.17.3.2 0.13
-
 xanthine
-
 Locusta sp.
1.17.3.2 0.26
-
 xanthine liver enzyme Gallus gallus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.17.3.2 Iron iron-molybdenum protein Gallus gallus
1.17.3.2 Iron iron-molybdenum protein Drosophila melanogaster
1.17.3.2 Iron iron-molybdenum protein Mus musculus
1.17.3.2 Iron iron-molybdenum protein Locusta sp.
1.17.3.2 Molybdenum an iron-molybdenum protein Gallus gallus
1.17.3.2 Molybdenum an iron-molybdenum protein Drosophila melanogaster
1.17.3.2 Molybdenum an iron-molybdenum protein Mus musculus
1.17.3.2 Molybdenum an iron-molybdenum protein Locusta sp.

Organism

EC Number Organism UniProt Comment Textmining
1.17.3.2 Drosophila melanogaster
-
-
-
1.17.3.2 Gallus gallus
-
-
-
1.17.3.2 Locusta sp.
-
-
-
1.17.3.2 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
1.17.3.2 additional information
-
 Gallus gallus
1.17.3.2 additional information
-
 Drosophila melanogaster
1.17.3.2 additional information
-
 Mus musculus
1.17.3.2 additional information
-
 Locusta sp.
1.17.3.2 proteolytic modification
-
 Gallus gallus
1.17.3.2 proteolytic modification
-
 Drosophila melanogaster
1.17.3.2 proteolytic modification
-
 Mus musculus
1.17.3.2 proteolytic modification
-
 Locusta sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.3.2 duodenum
-
 Mus musculus
-
1.17.3.2 duodenum
-
 Locusta sp.
-
1.17.3.2 kidney
-
 Mus musculus
-
1.17.3.2 kidney
-
 Locusta sp.
-
1.17.3.2 liver
-
 Gallus gallus
-
1.17.3.2 liver
-
 Mus musculus
-
1.17.3.2 liver
-
 Locusta sp.
-
1.17.3.2 lung
-
 Mus musculus
-
1.17.3.2 lung
-
 Locusta sp.
-
1.17.3.2 pancreas
-
 Mus musculus
-
1.17.3.2 pancreas
-
 Locusta sp.
-
1.17.3.2 spleen
-
 Mus musculus
-
1.17.3.2 spleen
-
 Locusta sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.3.2 2-amino-4-hydroxypteridine + H2O + O2
-
 Drosophila melanogaster ?
-
 r
1.17.3.2 2-amino-4-hydroxypteridine + H2O + O2
-
 Locusta sp. ?
-
 r
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
 Gallus gallus urate + 2 H2O2
-
 ?
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
 Drosophila melanogaster urate + 2 H2O2
-
 ?
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
 Mus musculus urate + 2 H2O2
-
 ?
1.17.3.2 hypoxanthine + 2 H2O + 2 O2
-
 Locusta sp. urate + 2 H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Gallus gallus uric acid + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Drosophila melanogaster uric acid + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Mus musculus uric acid + H2O2
-
 ?
1.17.3.2 xanthine + H2O + O2 electron acceptor O2 Locusta sp. uric acid + H2O2
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.17.3.2 7
-
-
 Locusta sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.3.2 FAD flavoprotein Gallus gallus
1.17.3.2 FAD flavoprotein Drosophila melanogaster
1.17.3.2 FAD flavoprotein Mus musculus
1.17.3.2 FAD flavoprotein Locusta sp.