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Literature summary extracted from

  • Edwards, T.C.R.; Candido, E.P.M.
    Xanthine dehydrogenase from Drosophila melanogaster. A comparison of the kinetic parameters of the pure enzyme from two wild-type isoalleles differing at a putative regulatory site (1977), Mol. Gen. Genet., 154, 1-6.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.17.1.4 0.024
-
xanthine ping-pong reaction mechanism Drosophila melanogaster
1.17.1.4 0.04
-
NAD+ ping-pong reaction mechanism Drosophila melanogaster

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.17.1.4 Mo
-
Drosophila melanogaster

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.17.1.4 150000
-
x * 150000, SDS-phosphate gel electrophoresis Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.1.4 hypoxanthine + NAD+ + H+ + O2- + H2O Drosophila melanogaster
-
xanthine + NADH + H2O2
-
?
1.17.1.4 xanthine + NAD+ + H2O Drosophila melanogaster
-
urate + NADH
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.17.1.4 Drosophila melanogaster
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.17.1.4 to homogeneity, immunoaffinity chromatography Drosophila melanogaster

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.1.4 hypoxanthine + NAD+ + H+ + O2- + H2O
-
Drosophila melanogaster xanthine + NADH + H2O2
-
?
1.17.1.4 xanthine + NAD+ + H2O
-
Drosophila melanogaster urate + NADH
-
?

Subunits

EC Number Subunits Comment Organism
1.17.1.4 ? x * 150000, SDS-phosphate gel electrophoresis Drosophila melanogaster

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.1.4 NAD+
-
Drosophila melanogaster