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Literature summary extracted from

  • Nichols, B.P.; Green, J.M.
    Cloning and sequencing of Escherichia coli ubiC and purification of chorismate lyase (1992), J. Bacteriol., 174, 5309-5316.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.39 gene cluster consisting of ubiC gene and a portion of ubiA is cloned and expressed in Escherichia coli Escherichia coli
4.1.3.40
-
 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.3.40 0.0097
-
 chorismate pH 7.5, 37°C Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.3.40 17000
-
 gel filtration Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.3.40 chorismate Escherichia coli first step in ubiquinone biosynthesis 4-hydroxybenzoate + pyruvate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.39 Escherichia coli
-
-
-
4.1.3.38 Escherichia coli
-
-
-
4.1.3.40 Escherichia coli P26602
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.3.40
-
 Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.3.38 4-amino-4-deoxychorismate
-
 Escherichia coli 4-aminobenzoate + pyruvate
-
 ?
4.1.3.40 chorismate
-
 Escherichia coli 4-hydroxybenzoate + pyruvate
-
 ?
4.1.3.40 chorismate first step in ubiquinone biosynthesis Escherichia coli 4-hydroxybenzoate + pyruvate
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.3.40 monomer 1 * 17000, SDS-PAGE Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
2.5.1.39 4-hydroxybenzoate octaprenyltransferase
-
 Escherichia coli
2.5.1.39 ubiA
-
 Escherichia coli
4.1.3.40 chorismate-pyruvate lyase
-
 Escherichia coli

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.1.3.40 0.82
-
 chorismate pH 7.5, 37°C Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.3.38 pyridoxal 5'-phosphate
-
 Escherichia coli