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Literature summary extracted from

  • Hall, A.
    Small GTP-binding proteins and the regulation of the actin cytoskeleton (1994), Annu. Rev. Cell Biol., 10, 31-54.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.6.5.2 GTPase activating protein GAP stimulating intrinsic GTPase acitivity Mammalia
3.6.5.2 guanine nucleotide exchange factor GEF
-
Mammalia

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.6.5.2 guanine nucleotide dissociation inhibitor GDI
-
Mammalia

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.6.5.2 GTP + H2O Mammalia
-
GDP + phosphate
-
ir
3.6.5.2 GTP + H2O Aplysia sp.
-
GDP + phosphate
-
ir

Organism

EC Number Organism UniProt Comment Textmining
3.6.5.2 Aplysia sp.
-
-
-
3.6.5.2 Mammalia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.6.5.2 GTP + H2O
-
Mammalia GDP + phosphate
-
ir
3.6.5.2 GTP + H2O
-
Aplysia sp. GDP + phosphate
-
ir