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Literature summary extracted from

  • Scovassi, A.I.; Plevani, P.; Bertazzoni, U.
    Eukaryotic DNA polymerases (1980), Trends Biochem. Sci., 1980, 335-337.
No PubMed abstract available

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.7 30000 50000 polymerase beta Mammalia
2.7.7.7 50000
-
 polymerase minor Trypanosoma brucei
2.7.7.7 70000
-
 polymerase II Tetrahymena pyriformis
2.7.7.7 80000 130000 polymerase I Tetrahymena pyriformis
2.7.7.7 100000
-
-
 Bos taurus
2.7.7.7 100000
-
 polymerase major Trypanosoma brucei
2.7.7.7 110000
-
-
 Homo sapiens
2.7.7.7 110000
-
 polymerase B Neurospora crassa
2.7.7.7 120000 200000 polymerase major Badhamia polycephala
2.7.7.7 130000
-
-
 Dictyostelium discoideum
2.7.7.7 130000 280000 polymerase alpha Mammalia
2.7.7.7 150000
-
-
 Bos taurus
2.7.7.7 150000
-
 polymerase A Neurospora crassa
2.7.7.7 150000
-
 polymerase I and II Saccharomyces cerevisiae
2.7.7.7 150000 300000 polymerase gamma and mitochondrial polymerase Mammalia
2.7.7.7 180000
-
-
 Mycosarcoma maydis
2.7.7.7 190000
-
-
 Homo sapiens
2.7.7.7 190000
-
 polymerase A Euglena gracilis
2.7.7.7 190000
-
 polymerase delta Mammalia
2.7.7.7 240000
-
 polymerase B Euglena gracilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn Mammalia
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Homo sapiens
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Saccharomyces cerevisiae
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Bos taurus
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Tetrahymena pyriformis
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Euglena gracilis
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Neurospora crassa
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Trypanosoma brucei
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Dictyostelium discoideum
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Badhamia polycephala
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Mycosarcoma maydis
-
 diphosphate + DNAn+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.7 Badhamia polycephala
-
-
-
2.7.7.7 Bos taurus
-
-
-
2.7.7.7 Dictyostelium discoideum
-
-
-
2.7.7.7 Euglena gracilis
-
-
-
2.7.7.7 Homo sapiens
-
-
-
2.7.7.7 Mammalia
-
-
-
2.7.7.7 Mycosarcoma maydis
-
-
-
2.7.7.7 Neurospora crassa
-
-
-
2.7.7.7 Saccharomyces cerevisiae
-
-
-
2.7.7.7 Tetrahymena pyriformis
-
-
-
2.7.7.7 Trypanosoma brucei
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Mammalia diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Homo sapiens diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Saccharomyces cerevisiae diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Bos taurus diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Tetrahymena pyriformis diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Euglena gracilis diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Neurospora crassa diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Trypanosoma brucei diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Dictyostelium discoideum diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Badhamia polycephala diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Mycosarcoma maydis diphosphate + DNAn+1
-
 ?