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Literature summary extracted from

  • Aoyagi, N.; Matsuoka, S.; Furunobu, A; Matsukage, A.; Sakaguchi, K.
    Drosophila DNA polymerase delta. Purification and characterization (1994), J. Biol. Chem., 169, 6045-5050.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.7.7 proliferating cell nuclear antigen
-
 Drosophila melanogaster

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.7 aphidicolin
-
 Drosophila melanogaster
2.7.7.7 KCl
-
 Drosophila melanogaster
2.7.7.7 N-ethylmaleimide
-
 Drosophila melanogaster

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.7 Mg2+ required Drosophila melanogaster

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.7 47000
-
 1 * 138000 + 1 * 47000, SDS-PAGE Drosophila melanogaster
2.7.7.7 138000
-
 1 * 138000 + 1 * 47000, SDS-PAGE Drosophila melanogaster
2.7.7.7 185000
-
 gel filtration Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn Drosophila melanogaster
-
 diphosphate + DNAn+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.7 Drosophila melanogaster
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.7 near homogeneity Drosophila melanogaster

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.7 embryo
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Drosophila melanogaster diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn exonuclease 3'--5' activity Drosophila melanogaster diphosphate + DNAn+1
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.7.7 dimer 1 * 138000 + 1 * 47000, SDS-PAGE Drosophila melanogaster

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.7 7.2
-
-
 Drosophila melanogaster

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.7.7 Drosophila melanogaster
-
-
 6.8