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Literature summary extracted from

  • Shioda, M.; Kano, K.; Kobayashi, M.; Kitagawa, I.; Shoji, M.; Yoshida, S.; Ikegami, S.
    Differential inhibition of eukaryotic DNA polymerases by halenaquinol sulfate, a p-hydroquinone sulfate obtained from a marine sponge (1994), FEBS Lett., 350, 249-252.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.7 Halenaquinol sulfate potential inhibitor of DNA polymerase alpha and epsilon, less effective against Escherichia coli DNA polymerase Escherichia coli
2.7.7.7 Halenaquinol sulfate potential inhibitor of DNA polymerase alpha and epsilon, less effective against Escherichia coli DNA polymerase Mammalia

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn Mammalia
-
 diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Escherichia coli
-
 diphosphate + DNAn+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.7 Escherichia coli
-
-
-
2.7.7.7 Mammalia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Mammalia diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Escherichia coli diphosphate + DNAn+1
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.7.7 additional information
-
 additional information
-
 Mammalia