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Literature summary extracted from

  • Weissbach, A.
    The functional roles of mammalian DNA polymerase (1979), Arch. Biochem. Biophys., 198, 386-396.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.7 aphidicolin
-
 Homo sapiens
2.7.7.7 aphidicolin
-
 Mammalia
2.7.7.7 Dideoxythymidine triphosphate
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn Mammalia overview: functional role of mammalian DNA polymerases diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn Homo sapiens overview: functional role of mammalian DNA polymerases diphosphate + DNAn+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.7 Homo sapiens
-
-
-
2.7.7.7 Mammalia
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.7 HeLa cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Mammalia diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn
-
 Homo sapiens diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn overview: functional role of mammalian DNA polymerases Mammalia diphosphate + DNAn+1
-
 ?
2.7.7.7 deoxynucleoside triphosphate + DNAn overview: functional role of mammalian DNA polymerases Homo sapiens diphosphate + DNAn+1
-
 ?