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Literature summary extracted from

  • Hanenberg, A.; Heim, S.; Wissing, J.B.; Wagner, K.G.
    Characterization of cytidine triphosphate:phosphatidate cytidyltransferase from suspension cultured Catharanthus roseus cells (1993), Plant Sci., 88, 13-18.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.7.41 ATP slight stimulation at high concentrations Catharanthus roseus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.41 ATP slight inhibition below 0.175 mM Catharanthus roseus
2.7.7.41 CDP
-
 Catharanthus roseus
2.7.7.41 diphosphate
-
 Catharanthus roseus
2.7.7.41 additional information no inhibition by 1.65 mM ADP Catharanthus roseus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.7.41 0.08
-
 phosphatidic acid pH 7.2, 37°C Catharanthus roseus
2.7.7.41 0.17
-
 CTP pH 7.2, 37°C Catharanthus roseus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.41 chloroplast envelope
-
 Catharanthus roseus 9941
-
2.7.7.41 endoplasmic reticulum
-
 Catharanthus roseus 5783
-
2.7.7.41 microsome
-
 Catharanthus roseus
-
-
2.7.7.41 plasma membrane
-
 Catharanthus roseus 5886
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.41 Ca2+ activates at low concentrations, decrease in activity at higher concentrations Catharanthus roseus
2.7.7.41 Co2+ activates at low concentrations, decrease in activity at higher concentrations Catharanthus roseus
2.7.7.41 Mg2+ maximal activation, about 15fold, at 10 mM Catharanthus roseus
2.7.7.41 Mn2+ maximal activation, about 10fold, at 1 mM Catharanthus roseus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.41 Catharanthus roseus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.41
-
 Catharanthus roseus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.41 cell suspension culture
-
 Catharanthus roseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.41 CTP + phosphatidate
-
 Catharanthus roseus diphosphate + CDPdiacylglycerol
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.41 7.3
-
-
 Catharanthus roseus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.7.41 0.24
-
 CDP pH 7.2, 37°C Catharanthus roseus
2.7.7.41 1.5
-
 diphosphate pH 7.2, 37°C Catharanthus roseus