EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.6.1 | ADP | the enzyme in MAU V cells is less sensitive than the enzyme in extracts of wild-type cells | Rattus norvegicus | |
2.7.6.1 | AMP | the enzyme in MAU V cells is less sensitive than the enzyme in extracts of wild-type cells, competitive with respect to ATP | Rattus norvegicus | |
2.7.6.1 | nucleotides | enzyme from HTC cells has an altered sensitivity to feedback inhibition by purine and pyrimidine nucleotides | Rattus norvegicus | |
2.7.6.1 | TDP | the enzyme in MAU V cells is less sensitive than the enzyme in extracts of wild-type cells, competitive with respect to ATP | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.6.1 | 0.008 | - |
phosphate | pH 7.4, 37ºC | Rattus norvegicus | |
2.7.6.1 | 0.045 | - |
ATP | pH 7.4, 37ºC | Rattus norvegicus | |
2.7.6.1 | 0.2 | - |
D-ribose 5-phosphate | pH 7.4, 37ºC | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.6.1 | Rattus norvegicus | - |
rat | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.6.1 | gel filtration | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.6.1 | HTC cell | cell line of rat hepatoma cells in continuous culture, clone MAU V with an inreased ability to salvage exogenous purines | Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.6.1 | 0.008 | - |
- |
Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.6.1 | ATP + D-ribose 5-phosphate | - |
Rattus norvegicus | AMP + 5-phospho-alpha-D-ribose 1-diphosphate | - |
? |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.6.1 | 37 | - |
assay at | Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.6.1 | 0.01 | - |
ADP | pH 7.4, 37ºC, wild-type cells | Rattus norvegicus | |
2.7.6.1 | 0.01 | - |
AMP | pH 7.4, 37ºC, wild-type cells | Rattus norvegicus | |
2.7.6.1 | 0.1 | - |
AMP | pH 7.4, 37ºC, MAU V cells | Rattus norvegicus | |
2.7.6.1 | 0.15 | - |
TDP | pH 7.4, 37ºC, wild-type cells | Rattus norvegicus | |
2.7.6.1 | 0.175 | - |
ADP | pH 7.4, 37ºC, MAU V cells | Rattus norvegicus | |
2.7.6.1 | 0.75 | - |
TDP | pH 7.4, 37ºC, MAU V cells | Rattus norvegicus |