Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Agarwal, K.C.; Parks, R.E.
    Inhibition of rat hepatic guanylate kinase by 6-thioguanosine-5-phosphate and 6-selenoguanosine-5-phosphate (1975), Biochem. Pharmacol., 24, 791-795.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.4.8 6-Selenoguanosine 5'-phosphate GMP-phosphorylation, pI 4.9-isozyme, competitive with respect to GMP Rattus norvegicus
2.7.4.8 6-Thioguanosine 5'-phosphate GMP-phosphorylation, pI 4.9-isozyme, competitive with respect to GMP Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.8 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.4.8 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.8 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.8 ATP + 8-azaguanosine 5'-monophosphate
-
 Rattus norvegicus ADP + 8-azaguanosine 5'-diphosphate
-
 ?
2.7.4.8 ATP + dGMP
-
 Rattus norvegicus ADP + dGDP
-
 r
2.7.4.8 dATP + dGMP
-
 Rattus norvegicus dADP + dGDP
-
 ?
2.7.4.8 dATP + GMP
-
 Rattus norvegicus dADP + GDP
-
 ?

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.4.8 Rattus norvegicus 3 isoelectric variants 4.8 4.7