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Literature summary extracted from

  • Font, B.; Gautherson, D.C.
    General and kinetic properties of pig heart mitochondrial adenylate kinase (1980), Biochim. Biophys. Acta, 611, 299-308.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.4.3 5,5'-dithiobis(2-nitrobenzoic acid) DTT reverses; not: mitochondrial enzyme Sus scrofa
2.7.4.3 AMP above 1 mM; substrate inhibition Sus scrofa
2.7.4.3 P1,P5-diadenosine 5'-pentaphosphate weak Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.4.3 cytosol cytosolic and mitochondrial kinases are distinct isozymes Sus scrofa 5829
-
2.7.4.3 mitochondrion intermembrane space Sus scrofa 5739
-
2.7.4.3 mitochondrion cytosolic and mitochondrial kinases are distinct isozymes Sus scrofa 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.4.3 Mg2+ requirement Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.3 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.4.3 partial Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.3 heart
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.3 ADP + ADP
-
 Sus scrofa ATP + AMP
-
 r
2.7.4.3 ATP + AMP best substrates Sus scrofa ADP + ADP
-
 r
2.7.4.3 ATP + AMP highly specific for AMP Sus scrofa ADP + ADP
-
 r
2.7.4.3 ATP + AMP no substrates are GMP, UMP, CMP Sus scrofa ADP + ADP
-
 r
2.7.4.3 ATP + AMP less specific for ATP Sus scrofa ADP + ADP
-
 r
2.7.4.3 CTP + AMP
-
 Sus scrofa ADP + CDP
-
 ?
2.7.4.3 GTP + AMP
-
 Sus scrofa ADP + GDP
-
 ?
2.7.4.3 UTP + AMP
-
 Sus scrofa ADP + UDP
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.4.3 30
-
 assay at Sus scrofa