EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.2.11 | A62T | drastic reduction in specific activity. 911fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | A62V | drastic reduction in specific activity. 188fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | D147G | reduction in catalytic activity. 2000fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | D162G | drastic reduction in specific activity. 611.1fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | D162N | drastic reduction in specific activity. 644fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | E153A | reduction in catalytic activity. 555.5fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | E153G | reduction in catalytic activity. 555.5fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | E153K | reduction in catalytic activity. 3444.4fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | I149F | drastic reduction in specific activity. 222.2fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | I149F | 222.2fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | I79T | reduction in catalytic activity. 21.1fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | L154S | reduction in catalytic activity. 1000fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | M94T | reduction in catalytic activity. 255.6fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
2.7.2.11 | S159P | reduction in catalytic activity. 211.1fold increase in Ki-value for L-Pro compared to wild-type enzyme | Solanum lycopersicum |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.2.11 | L-Pro | - |
Solanum lycopersicum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.2.11 | ATP + L-glutamate | Solanum lycopersicum | - |
ADP + L-glutamate 5-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.2.11 | Solanum lycopersicum | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.2.11 | ATP + L-glutamate | - |
Solanum lycopersicum | ADP + L-glutamate 5-phosphate | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.2.11 | 0.09 | - |
L-Pro | wild-type enzyme | Solanum lycopersicum | |
2.7.2.11 | 1.9 | - |
L-Pro | mutant enzyme I79T | Solanum lycopersicum | |
2.7.2.11 | 17 | - |
L-Pro | mutant enzyme A62V | Solanum lycopersicum | |
2.7.2.11 | 19 | - |
L-Pro | mutant enzyme S159P | Solanum lycopersicum | |
2.7.2.11 | 20 | - |
L-Pro | mutant enzyme I149F | Solanum lycopersicum | |
2.7.2.11 | 23 | - |
L-Pro | mutant enzyme M94T | Solanum lycopersicum | |
2.7.2.11 | 50 | - |
L-Pro | mutant enzyme E153A or E153G | Solanum lycopersicum | |
2.7.2.11 | 55 | - |
L-Pro | mutant enzyme D162G | Solanum lycopersicum | |
2.7.2.11 | 58 | - |
L-Pro | mutant enzyme D162N | Solanum lycopersicum | |
2.7.2.11 | 82 | - |
L-Pro | mutant enzyme A62T | Solanum lycopersicum | |
2.7.2.11 | 90 | - |
L-Pro | mutant enzyme L154S | Solanum lycopersicum | |
2.7.2.11 | 180 | - |
L-Pro | mutant enzyme D147G | Solanum lycopersicum | |
2.7.2.11 | 310 | - |
L-Pro | mutant enzyme E153K | Solanum lycopersicum |