Literature summary extracted from

Yu, Y.; Sreenivas, A.; Ostrander, D.B.; Carman, G.M.
Phosphorylation of Saccharomyces cerevisiae Choline Kinase on Ser30 and Ser85 by Protein Kinase A Regulates Phosphatidylcholine Synthesis by the CDP-choline Pathway (2002), J. Biol. Chem., 277, 34978-34986.

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.7.1.32	S30A	specific activity reduced by 44%, phosphorylation reduced by 70%	Saccharomyces cerevisiae
2.7.1.32	S30A/S85A	specific activity reduced by 60%, phosphorylation reduced by 83%	Saccharomyces cerevisiae
2.7.1.32	S85A	specific activity reduced by 8%, phosphorylation reduced by 17%	Saccharomyces cerevisiae

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.32	Saccharomyces cerevisiae	-	-	-

Posttranslational Modification

EC Number	Posttranslational Modification	Comment	Organism
2.7.1.32	additional information	enzyme activity is regulated via phosphorylation at S30 and/or S85 by protein kinase A	Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.32	ATP + choline	-	Saccharomyces cerevisiae	ADP + O-phosphocholine	-	?

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Release 2023.1 (January 2023)