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Literature summary extracted from

  • Sperry, J.F.; Robertson, D.C.
    Erythritol catabolism by Brucella abortus (1975), J. Bacteriol., 121, 619-630.
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.402 membrane
-
 Brucella abortus 16020
-
2.7.1.27 soluble
-
 Brucella abortus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.402 D-erythritol 1-phosphate + NAD+ Brucella abortus
-
 D-erythrulose 1-phosphate + NADH + H+
-
 ?
1.1.1.402 D-erythritol 1-phosphate + NAD+ Brucella abortus British 19
-
 D-erythrulose 1-phosphate + NADH + H+
-
 ?
2.7.1.27 ATP + erythritol Brucella abortus first step in erythritol metabolism ADP + L-erythritol 1-phosphate
-
 ?
2.7.1.27 ATP + erythritol Brucella abortus British 19 first step in erythritol metabolism ADP + L-erythritol 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.402 Brucella abortus
-
-
-
1.1.1.402 Brucella abortus British 19
-
-
-
2.7.1.27 Brucella abortus
-
-
-
2.7.1.215 Brucella abortus
-
-
-
2.7.1.215 Brucella abortus British 19
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.27 ammonium sulfate, Sephadex G-200 Brucella abortus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.402 D-erythritol 1-phosphate + NAD+
-
 Brucella abortus D-erythrulose 1-phosphate + NADH + H+
-
 ?
1.1.1.402 D-erythritol 1-phosphate + NAD+
-
 Brucella abortus British 19 D-erythrulose 1-phosphate + NADH + H+
-
 ?
2.7.1.27 ATP + erythritol first step in erythritol metabolism Brucella abortus ADP + L-erythritol 1-phosphate
-
 ?
2.7.1.27 ATP + erythritol first step in erythritol metabolism Brucella abortus British 19 ADP + L-erythritol 1-phosphate
-
 ?
2.7.1.27 ATP + erythritol
-
 Brucella abortus ADP + D-erythritol 1-phosphate i.e. L-erythritol-4-phosphate ?
2.7.1.27 ATP + erythritol
-
 Brucella abortus British 19 ADP + D-erythritol 1-phosphate i.e. L-erythritol-4-phosphate ?
2.7.1.215 ATP + erythritol
-
 Brucella abortus ADP + D-erythritol 1-phosphate
-
 ?
2.7.1.215 ATP + erythritol
-
 Brucella abortus British 19 ADP + D-erythritol 1-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.402 D-erythritol 1-phosphate dehydrogenase
-
 Brucella abortus
1.1.1.402 D-erythro-tetritol 1-phosphate:NAD 2-oxidoreductase
-
 Brucella abortus

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.402 NAD+ dependent on Brucella abortus

General Information

EC Number General Information Comment Organism
2.7.1.215 physiological function first reaction in the catbolism of erythritol is the phosphorylation of meso-erythritol with an ATP-dependent kinase which forms D-erythritol 1-phosphate Brucella abortus