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Literature summary extracted from

  • Okada, T.; Sakuma, L.; Fukui, Y.; Hazeki, O.; Ui, M.
    Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase (1994), J. Biol. Chem., 269, 3563-3567.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.137 Wortmannin inhibition is of a noncompetitive type with regard to ATP, observed with phosphatidylinositol, phosphatidylinositol monophosphate, or phosphatidylinositol bisphosphate as substrate Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.137 cytosol
-
Cavia porcellus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.137 additional information Cavia porcellus enzyme is involved in formyl peptide-induced stimulation of neutrophils ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.137 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.137 neutrophil
-
Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.137 ATP + 1-phosphatidylinositol
-
Cavia porcellus ADP + phosphatidylinositol 3-phosphate
-
?
2.7.1.137 additional information enzyme is involved in formyl peptide-induced stimulation of neutrophils Cavia porcellus ?
-
?