EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.11.14 | GRK1 from retina and pineal gland is cloned and sequenced | Gallus gallus |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.11.14 | C588S | unprenylated mutant | Bos taurus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.11.14 | 6 | - |
rhodopsin | farnesylated GRK1 | Bos taurus | |
2.7.11.14 | 9 | - |
rhodopsin | C588S mutant GRK1 | Bos taurus | |
2.7.11.14 | 30 | - |
rhodopsin | geranylgeranylated GRK1 | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.11.14 | membrane | membrane-bound | Bos taurus | 16020 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.14 | Mg2+ | - |
Bos taurus | |
2.7.11.14 | Mg2+ | - |
Gallus gallus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.11.14 | additional information | - |
amino acid sequence | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.14 | ATP + rhodopsin | Bos taurus | - |
ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | Gallus gallus | important enzyme of phototransduction | ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | Gallus gallus | light-dependent initiating of deactivation of rhodopsin | ADP + phosphorhodopsin | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.14 | Bos taurus | - |
- |
- |
2.7.11.14 | Gallus gallus | O73685 | - |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.7.11.14 | side-chain modification | native enzyme is farnesylated in vitro and in vivo | Bos taurus |
2.7.11.14 | side-chain modification | GRK1 contains a C-terminal consensus sequence for geranylgeranylation | Gallus gallus |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.11.14 | from whole retina | Gallus gallus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.14 | eye | retina | Bos taurus | - |
2.7.11.14 | eye | retina | Gallus gallus | - |
2.7.11.14 | pineal gland | - |
Bos taurus | - |
2.7.11.14 | pineal gland | young and adult | Gallus gallus | - |
2.7.11.14 | pineal gland | expression of retinal GRK1 | Gallus gallus | - |
2.7.11.14 | retina | - |
Bos taurus | - |
2.7.11.14 | retina | in rod and cone photoreceptors | Gallus gallus | - |
2.7.11.14 | retina | cone-dominant retina | Gallus gallus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.14 | ATP + rhodopsin | - |
Bos taurus | ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | phosphorylates bovine rhodopsin | Bos taurus | ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | phosphorylates bovine rhodopsin | Gallus gallus | ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | highly specific for photobleached rhodopsin | Bos taurus | ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | highly specific for photobleached rhodopsin | Gallus gallus | ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | important enzyme of phototransduction | Gallus gallus | ADP + phosphorhodopsin | - |
? | |
2.7.11.14 | ATP + rhodopsin | light-dependent initiating of deactivation of rhodopsin | Gallus gallus | ADP + phosphorhodopsin | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.11.14 | ? | - |
Bos taurus |
2.7.11.14 | ? | x * about 61000, SDS-PAGE | Gallus gallus |