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Literature summary extracted from

  • Chen, C.K.
    Recoverin and rhodopsin kinase (2002), Adv. Exp. Med. Biol., 514, 101-107.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.7.11.14 medicine Oguchi disease patients suffering from congenital stationary night blindness have defective RK or arrestin genes Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
2.7.11.14 additional information
-
 Homo sapiens
2.7.11.14 additional information RK knockout mice Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.14 recoverin Ca2+-dependent inhibition Mus musculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.14 Mg2+
-
 Mus musculus
2.7.11.14 Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.14 ATP + rhodopsin Homo sapiens
-
 ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin Mus musculus initiation of deactivation of photoexcited visual pigments in rod and cone photoreceptors, recoverin is a Ca2+-dependent negative regulator of RK in vertebrate phototransduction ADP + phosphorhodopsin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.14 Homo sapiens
-
-
-
2.7.11.14 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.14 eye retina Mus musculus
-
2.7.11.14 eye retina Homo sapiens
-
2.7.11.14 retina in rod and cone photoreceptors Mus musculus
-
2.7.11.14 retina in rod and cone photoreceptors Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.14 ATP + rhodopsin
-
 Homo sapiens ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin light-dependent phosphorylation Mus musculus ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin phosphorylates serine and threonine residues in the carboxy-terminal region of opsin peptide Mus musculus ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin initiation of deactivation of photoexcited visual pigments in rod and cone photoreceptors, recoverin is a Ca2+-dependent negative regulator of RK in vertebrate phototransduction Mus musculus ADP + phosphorhodopsin
-
 ?