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Literature summary extracted from

  • Doza, Y.N.; Minke, B.; Chorev, M.; Selinger, Z.
    Characterization of fly rhodopsin kinase (1992), Eur. J. Biochem., 209, 1035-1040.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.14 arrestin competes for binding to rhodopsin Musca domestica
2.7.11.14 G-protein competes for binding to rhodopsin Musca domestica
2.7.11.14 heparin potent inhibitor Musca domestica
2.7.11.14 additional information not: protein inhibitor of cAMP-dependent protein kinase Musca domestica
2.7.11.14 Urea
-
 Musca domestica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.11.14 0.009
-
 ATP pH 7.5, 20°C Musca domestica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.14 membrane membrane-bound Musca domestica 16020
-
2.7.11.14 membrane enzyme is released from rhodopsin-containing eye membranes Musca domestica 16020
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.14 Mg2+ requirement Musca domestica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.14 ATP + rhodopsin Musca domestica localization of enzyme enables it to quench immediately the activated form of the photopigment ADP + phosphorhodopsin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.14 Musca domestica
-
 fly
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.11.14 additional information enzyme may be posttranslationally modified Musca domestica

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.14 partial, 55fold Musca domestica

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.14 eye eye-specific, not in brain or abdomen Musca domestica
-

Storage Stability

EC Number Storage Stability Organism
2.7.11.14 -70°C, at least 3 months, stable Musca domestica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.14 ATP + Ac-RRRAAAAASAAA-NH2 synthetic peptide substrate Musca domestica ADP + Ac-RRRAAAAApSAAA-NH2
-
 ?
2.7.11.14 ATP + rhodopsin light-dependent phosphorylation Musca domestica ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin phosphorylates rhodopsin from Musca domestica, Lucilia cuprina and Drosophila melanogaster Musca domestica ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin preferred substrate: light-activated form of rhodopsin, i.e. metarhodopsin II Musca domestica ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin binds tightly to its substrate metarhodopsin and partially dissociates from rhodopsin Musca domestica ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin localization of enzyme enables it to quench immediately the activated form of the photopigment Musca domestica ADP + phosphorhodopsin
-
 ?
2.7.11.14 additional information almost inactive toward histone Musca domestica ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.11.14 20
-
 assay at Musca domestica

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.11.14 7.5
-
 assay at Musca domestica