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Literature summary extracted from

  • Stull, J.T.; Nunnally, M.H.; Michnoff, C.H in
    Calmoduline-dependent protein kinases (1986), The Enzymes, 3rd. Ed. (Boyer, P. D. , Krebs, E. G. , eds. ), 17, 113-166.
No PubMed abstract available

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.11.18 additional information
-
additional information kinetic constants for enzymes from various sources with different myosin light chains as substrates Gallus gallus
2.7.11.18 additional information
-
additional information kinetic constants for enzymes from various sources with different myosin light chains as substrates Meleagris gallopavo
2.7.11.18 additional information
-
additional information kinetic constants for enzymes from various sources with different myosin light chains as substrates Cavia porcellus
2.7.11.18 additional information
-
additional information kinetic constants for enzymes from various sources with different myosin light chains as substrates Homo sapiens
2.7.11.18 additional information
-
additional information kinetic constants for enzymes from various sources with different myosin light chains as substrates Rattus norvegicus
2.7.11.18 additional information
-
additional information kinetic constants for enzymes from various sources with different myosin light chains as substrates Bos taurus
2.7.11.18 additional information
-
additional information kinetic constants for enzymes from various sources with different myosin light chains as substrates Canis lupus familiaris

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.18 Ca2+
-
Gallus gallus
2.7.11.18 Ca2+
-
Meleagris gallopavo
2.7.11.18 Ca2+
-
Cavia porcellus
2.7.11.18 Ca2+
-
Homo sapiens
2.7.11.18 Ca2+
-
Rattus norvegicus
2.7.11.18 Ca2+
-
Bos taurus
2.7.11.18 Ca2+
-
Canis lupus familiaris

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.18 additional information
-
different molecular weights may be due to high sensitivity to proteolysis during purification Gallus gallus
2.7.11.18 additional information
-
different molecular weights may be due to high sensitivity to proteolysis during purification Meleagris gallopavo
2.7.11.18 additional information
-
different molecular weights may be due to high sensitivity to proteolysis during purification Cavia porcellus
2.7.11.18 additional information
-
different molecular weights may be due to high sensitivity to proteolysis during purification Homo sapiens
2.7.11.18 additional information
-
different molecular weights may be due to high sensitivity to proteolysis during purification Rattus norvegicus
2.7.11.18 additional information
-
different molecular weights may be due to high sensitivity to proteolysis during purification Bos taurus
2.7.11.18 additional information
-
different molecular weights may be due to high sensitivity to proteolysis during purification Canis lupus familiaris
2.7.11.18 additional information
-
relative masses of various animal skeletal muscle enzymes Gallus gallus
2.7.11.18 additional information
-
relative masses of various animal skeletal muscle enzymes Meleagris gallopavo
2.7.11.18 additional information
-
relative masses of various animal skeletal muscle enzymes Cavia porcellus
2.7.11.18 additional information
-
relative masses of various animal skeletal muscle enzymes Homo sapiens
2.7.11.18 additional information
-
relative masses of various animal skeletal muscle enzymes Rattus norvegicus
2.7.11.18 additional information
-
relative masses of various animal skeletal muscle enzymes Bos taurus
2.7.11.18 additional information
-
relative masses of various animal skeletal muscle enzymes Canis lupus familiaris
2.7.11.18 124000
-
sedimentation equilibrium centrifugation Meleagris gallopavo
2.7.11.18 130000
-
1 * 130000, SDS-PAGE Meleagris gallopavo

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.18 ATP + myosin light chain Gallus gallus involved in muscle contractility and motility of non-muscle cells ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain Meleagris gallopavo involved in muscle contractility and motility of non-muscle cells ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain Cavia porcellus involved in muscle contractility and motility of non-muscle cells ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain Homo sapiens involved in muscle contractility and motility of non-muscle cells ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain Rattus norvegicus involved in muscle contractility and motility of non-muscle cells ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain Bos taurus involved in muscle contractility and motility of non-muscle cells ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain Canis lupus familiaris involved in muscle contractility and motility of non-muscle cells ADP + myosin light chain phosphate
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Bos taurus
-
steer
-
2.7.11.18 Canis lupus familiaris
-
-
-
2.7.11.18 Cavia porcellus
-
-
-
2.7.11.18 Gallus gallus
-
-
-
2.7.11.18 Homo sapiens
-
-
-
2.7.11.18 Meleagris gallopavo
-
-
-
2.7.11.18 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.18 purified to homogeneity from a number of vertebrate muscles and partially purified from non-muscle tissues Gallus gallus
2.7.11.18 purified to homogeneity from a number of vertebrate muscles and partially purified from non-muscle tissues Meleagris gallopavo
2.7.11.18 purified to homogeneity from a number of vertebrate muscles and partially purified from non-muscle tissues Cavia porcellus
2.7.11.18 purified to homogeneity from a number of vertebrate muscles and partially purified from non-muscle tissues Homo sapiens
2.7.11.18 purified to homogeneity from a number of vertebrate muscles and partially purified from non-muscle tissues Rattus norvegicus
2.7.11.18 purified to homogeneity from a number of vertebrate muscles and partially purified from non-muscle tissues Bos taurus
2.7.11.18 purified to homogeneity from a number of vertebrate muscles and partially purified from non-muscle tissues Canis lupus familiaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.18 cardiac muscle
-
Bos taurus
-
2.7.11.18 gizzard
-
Gallus gallus
-
2.7.11.18 gizzard
-
Meleagris gallopavo
-
2.7.11.18 platelet
-
Homo sapiens
-
2.7.11.18 skeletal muscle red and white Gallus gallus
-
2.7.11.18 skeletal muscle red and white Meleagris gallopavo
-
2.7.11.18 skeletal muscle red and white Cavia porcellus
-
2.7.11.18 skeletal muscle red and white Homo sapiens
-
2.7.11.18 skeletal muscle red and white Rattus norvegicus
-
2.7.11.18 skeletal muscle red and white Bos taurus
-
2.7.11.18 skeletal muscle red and white Canis lupus familiaris
-
2.7.11.18 smooth muscle
-
Gallus gallus
-
2.7.11.18 smooth muscle
-
Meleagris gallopavo
-
2.7.11.18 smooth muscle
-
Cavia porcellus
-
2.7.11.18 smooth muscle
-
Homo sapiens
-
2.7.11.18 smooth muscle
-
Rattus norvegicus
-
2.7.11.18 smooth muscle
-
Bos taurus
-
2.7.11.18 smooth muscle
-
Canis lupus familiaris
-
2.7.11.18 thyroid gland
-
Gallus gallus
-
2.7.11.18 thyroid gland
-
Meleagris gallopavo
-
2.7.11.18 thyroid gland
-
Cavia porcellus
-
2.7.11.18 thyroid gland
-
Homo sapiens
-
2.7.11.18 thyroid gland
-
Rattus norvegicus
-
2.7.11.18 thyroid gland
-
Bos taurus
-
2.7.11.18 thyroid gland
-
Canis lupus familiaris
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.18 ATP + myosin light chain no substrates are myosin heavy chain and phosvitin Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrates are myosin heavy chain and phosvitin Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrates are myosin heavy chain and phosvitin Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrates are myosin heavy chain and phosvitin Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrates are myosin heavy chain and phosvitin Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrates are myosin heavy chain and phosvitin Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrates are myosin heavy chain and phosvitin Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of skeletal muscle Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of skeletal muscle Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of skeletal muscle Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of skeletal muscle Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of skeletal muscle Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of skeletal muscle Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of skeletal muscle Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of non-muscle myosin Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of non-muscle myosin Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of non-muscle myosin Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of non-muscle myosin Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of non-muscle myosin Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of non-muscle myosin Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of non-muscle myosin Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain not specific for 22 kDa and 15 kDa light chain Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain not specific for 22 kDa and 15 kDa light chain Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain not specific for 22 kDa and 15 kDa light chain Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain not specific for 22 kDa and 15 kDa light chain Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain not specific for 22 kDa and 15 kDa light chain Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain not specific for 22 kDa and 15 kDa light chain Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain not specific for 22 kDa and 15 kDa light chain Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is casein Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is casein Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is casein Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is casein Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is casein Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is casein Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is casein Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is troponin Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is troponin Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is troponin Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is troponin Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is troponin Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is troponin Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is troponin Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase kinase Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase kinase Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase kinase Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase kinase Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase kinase Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase kinase Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase kinase Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain kinase from skeletal muscle with broader specificity than smooth muscle kinase Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain kinase from skeletal muscle with broader specificity than smooth muscle kinase Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain kinase from skeletal muscle with broader specificity than smooth muscle kinase Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain kinase from skeletal muscle with broader specificity than smooth muscle kinase Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain kinase from skeletal muscle with broader specificity than smooth muscle kinase Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain kinase from skeletal muscle with broader specificity than smooth muscle kinase Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain kinase from skeletal muscle with broader specificity than smooth muscle kinase Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain involved in muscle contractility and motility of non-muscle cells Gallus gallus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain involved in muscle contractility and motility of non-muscle cells Meleagris gallopavo ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain involved in muscle contractility and motility of non-muscle cells Cavia porcellus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain involved in muscle contractility and motility of non-muscle cells Homo sapiens ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain involved in muscle contractility and motility of non-muscle cells Rattus norvegicus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain involved in muscle contractility and motility of non-muscle cells Bos taurus ADP + myosin light chain phosphate
-
?
2.7.11.18 ATP + myosin light chain involved in muscle contractility and motility of non-muscle cells Canis lupus familiaris ADP + myosin light chain phosphate
-
?
2.7.11.18 additional information skeletal, gizzard smooth and cardiac enzymes perform intramolecular autophosphorylation in the absence of acceptor substrate Gallus gallus ?
-
?
2.7.11.18 additional information skeletal, gizzard smooth and cardiac enzymes perform intramolecular autophosphorylation in the absence of acceptor substrate Cavia porcellus ?
-
?
2.7.11.18 additional information skeletal, gizzard smooth and cardiac enzymes perform intramolecular autophosphorylation in the absence of acceptor substrate Homo sapiens ?
-
?
2.7.11.18 additional information skeletal, gizzard smooth and cardiac enzymes perform intramolecular autophosphorylation in the absence of acceptor substrate Rattus norvegicus ?
-
?
2.7.11.18 additional information skeletal, gizzard smooth and cardiac enzymes perform intramolecular autophosphorylation in the absence of acceptor substrate Bos taurus ?
-
?
2.7.11.18 additional information skeletal, gizzard smooth and cardiac enzymes perform intramolecular autophosphorylation in the absence of acceptor substrate Canis lupus familiaris ?
-
?

Subunits

EC Number Subunits Comment Organism
2.7.11.18 monomer
-
Gallus gallus
2.7.11.18 monomer
-
Cavia porcellus
2.7.11.18 monomer
-
Homo sapiens
2.7.11.18 monomer
-
Rattus norvegicus
2.7.11.18 monomer
-
Bos taurus
2.7.11.18 monomer
-
Canis lupus familiaris
2.7.11.18 monomer 1 * 130000, SDS-PAGE Meleagris gallopavo
2.7.11.18 More different molecular weights may be due to high sensitivity to proteolysis during purification Gallus gallus
2.7.11.18 More different molecular weights may be due to high sensitivity to proteolysis during purification Meleagris gallopavo
2.7.11.18 More different molecular weights may be due to high sensitivity to proteolysis during purification Cavia porcellus
2.7.11.18 More different molecular weights may be due to high sensitivity to proteolysis during purification Homo sapiens
2.7.11.18 More different molecular weights may be due to high sensitivity to proteolysis during purification Rattus norvegicus
2.7.11.18 More different molecular weights may be due to high sensitivity to proteolysis during purification Bos taurus
2.7.11.18 More different molecular weights may be due to high sensitivity to proteolysis during purification Canis lupus familiaris

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.18 Calmodulin requirement Gallus gallus
2.7.11.18 Calmodulin requirement Meleagris gallopavo
2.7.11.18 Calmodulin requirement Cavia porcellus
2.7.11.18 Calmodulin requirement Homo sapiens
2.7.11.18 Calmodulin requirement Rattus norvegicus
2.7.11.18 Calmodulin requirement Bos taurus
2.7.11.18 Calmodulin requirement Canis lupus familiaris
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Gallus gallus
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Meleagris gallopavo
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Cavia porcellus
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Homo sapiens
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Rattus norvegicus
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Bos taurus
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Canis lupus familiaris
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Gallus gallus
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Meleagris gallopavo
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Cavia porcellus
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Homo sapiens
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Rattus norvegicus
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Bos taurus
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Canis lupus familiaris