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Literature summary extracted from

  • Labenz, J.; Müller, W.E.G.; Falke, D.
    Inhibition of the Herpes simplex virus-coded thymidine kinase-complex by 9-beta-D-arabinofuranosyladenine 5-monophosphate (ara-AMP) and 9-(2-hydroxyethoxymethyl)guanine-monophosphate (acyclo-GMP) (1984), Arch. Virol., 81, 205-212.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.114 9-beta-D-Arabinofuranosyladenine 5'-monophosphate
-
Herpes simplex virus
2.7.1.118 9-(2-Hydroxyethoxymethyl)guanino monophosphate i.e. acyclo-GMP Herpes simplex virus
2.7.1.118 9-beta-D-Arabinofuranosyladenine 5'-monophosphate
-
Herpes simplex virus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.114 AMP + thymidine Herpes simplex virus
-
adenosine + dTMP
-
?
2.7.1.118 ADP + thymidine Herpes simplex virus
-
AMP + dTMP
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.114 Herpes simplex virus
-
type 1
-
2.7.1.118 Herpes simplex virus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.118 virus type 1, partial Herpes simplex virus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.114 AMP + thymidine
-
Herpes simplex virus adenosine + dTMP
-
?
2.7.1.118 ADP + thymidine
-
Herpes simplex virus AMP + dTMP
-
?