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Literature summary extracted from

  • Isaac, J.E.; Rhodes, M.J.C.
    Phosphofructokinase from Lycopersicon esculentum fruits-I. Kinetic properties in relation to its substrates (1986), Phytochemistry, 25, 339-343.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.11 ATP above 1 mM, inhibition is relieved by Mg2+; free form Solanum lycopersicum
2.7.1.11 CTP free form, Mg2+ relieves Solanum lycopersicum
2.7.1.11 GTP free form, Mg2+ relieves Solanum lycopersicum
2.7.1.11 additional information not inhibited by MgATP2- Solanum lycopersicum
2.7.1.11 UTP free form, Mg2+ relieves Solanum lycopersicum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.11 additional information
-
 additional information kinetic study Solanum lycopersicum
2.7.1.11 additional information
-
 additional information oligomeric form exhibits negative cooperativity with fructose 6-phosphate Solanum lycopersicum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.11 Mg2+ required for activity Solanum lycopersicum
2.7.1.11 Mg2+ maximal activity at 5 mM, Km-value: 0.84 mM Solanum lycopersicum
2.7.1.11 Mg2+ MgATP is the active substrate Solanum lycopersicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.11 ATP + D-fructose 6-phosphate Solanum lycopersicum allosteric enzyme, involved in regulation of glycolytic flux ADP + D-fructose 1,6-bisphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.11 Solanum lycopersicum
-
 tomato, var. Eurocross BB
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.11 fruit
-
 Solanum lycopersicum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.11 ATP + D-fructose 6-phosphate
-
 Solanum lycopersicum ADP + D-fructose 1,6-bisphosphate
-
 ?
2.7.1.11 ATP + D-fructose 6-phosphate allosteric enzyme, involved in regulation of glycolytic flux Solanum lycopersicum ADP + D-fructose 1,6-bisphosphate
-
 ?
2.7.1.11 CTP + D-fructose 6-phosphate less effective than ATP Solanum lycopersicum CDP + D-fructose 1,6-bisphosphate
-
 ?
2.7.1.11 GTP + D-fructose 6-phosphate almost as effective as ATP Solanum lycopersicum GDP + D-fructose 1,6-bisphosphate
-
 ?
2.7.1.11 ITP + D-fructose 6-phosphate less effective than ATP Solanum lycopersicum IDP + D-fructose 1,6-bisphosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.11 25
-
 assay at Solanum lycopersicum