Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Röber, B.; Stolle, J.; Reuter, G.
    Eigenschaften der Hexokinase aus der SCP Hefe Candida maltosa H (1984), Z. Allg. Mikrobiol., 24, 619-627.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.1 galactose activates isoenzyme Hex II Candida maltosa
2.7.1.1 isocitrate activates isoenzyme Hex II Candida maltosa
2.7.1.1 lyxose activates isoenzyme Hex II Candida maltosa
2.7.1.1 mannose 6-phosphate activates isoenzyme Hex II Candida maltosa
2.7.1.1 phosphoenolpyruvate activates isoenzyme Hex I Candida maltosa
2.7.1.1 ribose activates isoenzyme Hex II Candida maltosa
2.7.1.1 xylose activates isoenzyme Hex II Candida maltosa

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.1 ADP
-
Candida maltosa
2.7.1.1 D-mannose
-
Candida maltosa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.1 additional information
-
additional information
-
Candida maltosa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.1 Mg2+ required Candida maltosa
2.7.1.1 Mg2+ below 3 mM Candida maltosa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.1 96000
-
Hex II, gel filtration Candida maltosa
2.7.1.1 110000
-
gel filtration Candida maltosa
2.7.1.1 110000
-
Hex I Candida maltosa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.1 D-glucose + ATP Candida maltosa isoenzymes are a target for effective control of glucose 6-phosphate formation by energy charge of the cell or by the intracellular level of ATP, ADP and glucose instead of allosteric interconversions of the enzyme D-glucose 6-phosphate + ADP
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.1 Candida maltosa
-
H, isoenzymes Hex I and Hex II
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.1 isoenzymes Hex I and Hex II, partial Candida maltosa

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.1 additional information
-
-
Candida maltosa
2.7.1.1 0.11 0.16 Hex I and II, at pH 8.2 Candida maltosa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.1 D-glucose + ATP specific for ATP Candida maltosa ADP + D-glucose 6-phosphate
-
?
2.7.1.1 D-glucose + ATP isoenzymes are a target for effective control of glucose 6-phosphate formation by energy charge of the cell or by the intracellular level of ATP, ADP and glucose instead of allosteric interconversions of the enzyme Candida maltosa D-glucose 6-phosphate + ADP
-
?
2.7.1.1 D-mannose + ATP
-
Candida maltosa ADP + D-mannose 6-phosphate
-
?
2.7.1.1 additional information not: UTP Candida maltosa ?
-
?
2.7.1.1 additional information not: ITP Candida maltosa ?
-
?
2.7.1.1 additional information not: GTP Candida maltosa ?
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.1 7.5 8.5 isoenzyme Hex II Candida maltosa
2.7.1.1 7.5 8.2 isoenzyme Hex I Candida maltosa
2.7.1.1 8.2
-
assay at Candida maltosa

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.1 ATP
-
Candida maltosa