Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Simpson, R.J.; Davidson, B.E.
    Studies on 3-deoxy-D-arabinoheptulosonate-7-phosphate synthetase(phe) from Escherichia coli K12. 3. Structural studies (1976), Eur. J. Biochem., 70, 509-516.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.5.1.54 additional information sulfhydryl groups and possibly a Lys residue may be implicated in activity Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.54 5,5'-dithiobis(2-nitrobenzoate)
-
 Escherichia coli
2.5.1.54 alpha-Methylphenylalanine
-
 Escherichia coli
2.5.1.54 beta-phenylserine
-
 Escherichia coli
2.5.1.54 beta-Thienylalanine
-
 Escherichia coli
2.5.1.54 m-Chlorophenylalanine
-
 Escherichia coli
2.5.1.54 m-Fluorophenylalanine
-
 Escherichia coli
2.5.1.54 m-hydroxyphenylalanine
-
 Escherichia coli
2.5.1.54 N-bromosuccinimide
-
 Escherichia coli
2.5.1.54 N-ethylmaleimide
-
 Escherichia coli
2.5.1.54 o-chlorophenylalanine
-
 Escherichia coli
2.5.1.54 o-Fluorophenylalanine
-
 Escherichia coli
2.5.1.54 o-hydroxyphenylalanine
-
 Escherichia coli
2.5.1.54 p-aminophenylalanine
-
 Escherichia coli
2.5.1.54 p-Fluorophenylalanine
-
 Escherichia coli
2.5.1.54 Phe L-Phe; Phe-sensitive isozyme Escherichia coli
2.5.1.54 Tetranitromethane
-
 Escherichia coli
2.5.1.54 Trinitrobenzene sulfonate
-
 Escherichia coli
2.5.1.54 Tyr L-Tyr; Tyr-sensitive isozyme Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.54 Escherichia coli
-
 K12
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.54 phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
 Escherichia coli 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
 ?