Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Radabaugh, T.R.; Aposhian, H.V.
    Enzymatic reduction of arsenic compounds in mammalian systems Reduction of arsenate to arsenite by human liver arsenate reductase (2000), Chem. Res. Toxicol., 200; 13, 26-30.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.20.99.1 additional information heat stable cofactor is required Homo sapiens
1.20.99.1 thiol required for activity, thiol requirement can be satisfied by dithiothreitol, stimulation by glutathione, thioredoxin or reduced lipoc acid is negligible compared to that of dithiothreitol Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.20.99.1 71800
-
gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.20.99.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.20.99.1 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.20.99.1 liver
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.20.99.1 0.0007
-
-
Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.20.99.1 arsenate + ?
-
Homo sapiens arsenite + ?
-
?