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Literature summary extracted from

  • Charon, L.; Pale-Grosdemange, C.; Rohmer, M.
    On the reduction steps in the mevalonate independent 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in the bacterium Zymomonas mobilis (1999), Tetrahedron Lett., 40, 7231-7234.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.7.4 (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ Zymomonas mobilis
-
dimethylallyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
r
1.17.7.4 isopentenyl diphosphate + NAD(P)+ + H2O Zymomonas mobilis 2-C-methyl-D-erithritol-4-phosphate pathway (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
-
r

Organism

EC Number Organism UniProt Comment Textmining
1.17.7.4 Zymomonas mobilis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.7.4 (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+
-
Zymomonas mobilis isopentenyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
r
1.17.7.4 (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+
-
Zymomonas mobilis dimethylallyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
r
1.17.7.4 (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+
-
Zymomonas mobilis dimethylallyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O dimethylallyl diphosphate is convertable into isopentenyl diphosphate and vice versa r
1.17.7.4 isopentenyl diphosphate + NAD(P)+ + H2O 2-C-methyl-D-erithritol-4-phosphate pathway Zymomonas mobilis (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
-
r

Cofactor

EC Number Cofactor Comment Organism Structure
1.17.7.4 NAD+
-
Zymomonas mobilis
1.17.7.4 NADH
-
Zymomonas mobilis
1.17.7.4 NADP+
-
Zymomonas mobilis
1.17.7.4 NADPH
-
Zymomonas mobilis