EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.18.2 | 0.005 | - |
CMP-N-acetylneuraminate | pH 7.4, 37°C, amphiphilic system | Mus musculus | |
1.14.18.2 | 0.013 | - |
CMP-N-acetylneuraminate | pH 7.4, 37°C, soluble system | Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.18.2 | microsome | - |
Mus musculus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.14.18.2 | 58000 | - |
gel filtration | Mus musculus |
1.14.18.2 | 64000 | - |
1 * 64000, SDS-PAGE | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.18.2 | CMP-N-acetylneuraminate + NADH + O2 | Mus musculus | a regulation of CMP-N-acetylneuraminate hydroxylation and thus the ratio of glycoconjugate-bound N-acetylneuraminate and N-acetylglycoloylneuraminate might occur by varying the amount of hydroxylase protein within the cell, possibly by controlling the expression of the hydroxylase gene | CMP-N-glycoloylneuraminate + NAD+ + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.18.2 | Mus musculus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.18.2 | - |
Mus musculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.18.2 | liver | - |
Mus musculus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.14.18.2 | 0.126 | - |
- |
Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.18.2 | CMP-N-acetylneuraminate + ferrocytochrome b5 + O2 | - |
Mus musculus | CMP-N-glycoloylneuraminate + ferricytrochrome b5 + H2O | - |
? | |
1.14.18.2 | CMP-N-acetylneuraminate + NADH + O2 | - |
Mus musculus | CMP-N-glycoloylneuraminate + NAD+ + H2O | - |
? | |
1.14.18.2 | CMP-N-acetylneuraminate + NADH + O2 | a regulation of CMP-N-acetylneuraminate hydroxylation and thus the ratio of glycoconjugate-bound N-acetylneuraminate and N-acetylglycoloylneuraminate might occur by varying the amount of hydroxylase protein within the cell, possibly by controlling the expression of the hydroxylase gene | Mus musculus | CMP-N-glycoloylneuraminate + NAD+ + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.18.2 | monomer | 1 * 64000, SDS-PAGE | Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.2 | NADH | - |
Mus musculus |