Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ekegren, T.; Aquilonius, S.M.; Gomes-Trolin, C.
    A comparative study of methionine adenosyltransferase activity and regional distribution in mammalian spinal cord (2000), Biochem. Pharmacol., 60, 441-445.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.5.1.6 significant decrease during the interval from 0-8 hr at 23ºC after decapitation. From here up to 72 hs post-mortem at 4ºC the activity remains at 60% of the initial value Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.6 0.0029
-
 L-methionine
-
 Felis catus
2.5.1.6 0.003
-
 L-methionine
-
 Macaca mulatta

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.6 Bos taurus
-
-
-
2.5.1.6 Felis catus
-
 cat
-
2.5.1.6 Macaca mulatta
-
-
-
2.5.1.6 Rattus norvegicus
-
 Sprague-Dawley rats
-
2.5.1.6 Sus scrofa
-
 pig
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.5.1.6 spinal cord
-
 Rattus norvegicus
-
2.5.1.6 spinal cord
-
 Sus scrofa
-
2.5.1.6 spinal cord
-
 Bos taurus
-
2.5.1.6 spinal cord
-
 Felis catus
-
2.5.1.6 spinal cord
-
 Macaca mulatta
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.6 ATP + L-methionine + H2O
-
 Rattus norvegicus S-adenosyl-L-methionine + phosphate + diphosphate
-
 ?
2.5.1.6 ATP + L-methionine + H2O
-
 Sus scrofa S-adenosyl-L-methionine + phosphate + diphosphate
-
 ?
2.5.1.6 ATP + L-methionine + H2O
-
 Bos taurus S-adenosyl-L-methionine + phosphate + diphosphate
-
 ?
2.5.1.6 ATP + L-methionine + H2O
-
 Felis catus S-adenosyl-L-methionine + phosphate + diphosphate
-
 ?
2.5.1.6 ATP + L-methionine + H2O
-
 Macaca mulatta S-adenosyl-L-methionine + phosphate + diphosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.5.1.6 37
-
 assay at Rattus norvegicus
2.5.1.6 37
-
 assay at Sus scrofa
2.5.1.6 37
-
 assay at Bos taurus
2.5.1.6 37
-
 assay at Felis catus
2.5.1.6 37
-
 assay at Macaca mulatta

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.5.1.6 7.7
-
 assay at Sus scrofa
2.5.1.6 7.7
-
 assay at Bos taurus
2.5.1.6 7.7
-
 assay at Felis catus
2.5.1.6 7.7
-
 assay at Macaca mulatta