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Literature summary extracted from

  • Sundaram, T.K.; Chell, R.M.; Wilkinson, A.E.
    Monomeric malate synthase from a thermophilic Bacillus (1980), Arch. Biochem. Biophys., 199, 515-525.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.3.9 glycolate
-
 Bacillus sp. (in: Bacteria)
2.3.3.9 oxalate
-
 Bacillus sp. (in: Bacteria)

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.3.9 0.008
-
 acetyl-CoA
-
 Bacillus sp. (in: Bacteria)
2.3.3.9 0.058
-
 glyoxylate
-
 Bacillus sp. (in: Bacteria)

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.3.9 58000
-
 1 * 58000, SDS-PAGE Bacillus sp. (in: Bacteria)
2.3.3.9 62000
-
 gel filtration Neurospora crassa
2.3.3.9 62000
-
 gel filtration Bacillus sp. (in: Bacteria)
2.3.3.9 160000
-
 gel filtration Neurospora crassa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.3.9 glyoxylate + acetyl-CoA + H2O Escherichia coli enzyme specifically involved in glyoxalate cycle metabolism (S)-malate + CoA
-
 ?
2.3.3.9 glyoxylate + acetyl-CoA + H2O Bacillus sp. (in: Bacteria) enzyme specifically involved in glyoxalate cycle metabolism (S)-malate + CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.3.9 Bacillus sp. (in: Bacteria)
-
 thermophilic
-
2.3.3.9 Escherichia coli
-
-
-
2.3.3.9 Neurospora crassa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.3.9
-
 Bacillus sp. (in: Bacteria)

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.3.9 cotyledon
-
 Bacillus sp. (in: Bacteria)
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.3.9 glyoxylate + acetyl-CoA + H2O
-
 Escherichia coli (S)-malate + CoA
-
 ?
2.3.3.9 glyoxylate + acetyl-CoA + H2O
-
 Neurospora crassa (S)-malate + CoA
-
 ?
2.3.3.9 glyoxylate + acetyl-CoA + H2O
-
 Bacillus sp. (in: Bacteria) (S)-malate + CoA
-
 ?
2.3.3.9 glyoxylate + acetyl-CoA + H2O enzyme specifically involved in glyoxalate cycle metabolism Escherichia coli (S)-malate + CoA
-
 ?
2.3.3.9 glyoxylate + acetyl-CoA + H2O enzyme specifically involved in glyoxalate cycle metabolism Bacillus sp. (in: Bacteria) (S)-malate + CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.3.9 monomer
-
 Escherichia coli
2.3.3.9 monomer
-
 Neurospora crassa
2.3.3.9 monomer 1 * 58000, SDS-PAGE Bacillus sp. (in: Bacteria)
2.3.3.9 More enzyme monomeric in procaryotes but multimeric in eucaryotes Escherichia coli
2.3.3.9 More enzyme monomeric in procaryotes but multimeric in eucaryotes Neurospora crassa

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.3.3.9 27.8
-
 acetyl-CoA
-
 Bacillus sp. (in: Bacteria)

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.3.9 additional information
-
 4.6 Bacillus sp. (in: Bacteria)
2.3.3.9 8.6
-
-
 Bacillus sp. (in: Bacteria)

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.3.9 0.07
-
 glycolate
-
 Bacillus sp. (in: Bacteria)
2.3.3.9 0.09
-
 oxalate
-
 Bacillus sp. (in: Bacteria)