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Literature summary extracted from

  • Yang, Q.; Yoshimura, G.; Mori, I.; Sakurai, T.; Kakudo, K.
    Thymidine phosphorylase and breast carcinoma (2002), Anticancer Res., 22, 2355-2360.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.2.4
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.4 5-bromo-6-aminouracil
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.2.4 45000
-
 SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.4 additional information Homo sapiens formation of blood/brain barrier and repair following brain injury ?
-
 ?
2.4.2.4 additional information Homo sapiens angiogenic activity ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.4 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.4 blood platelet
-
 Homo sapiens
-
2.4.2.4 breast ductal carcinoma in situ and invasive elements Homo sapiens
-
2.4.2.4 colonic cancer cell
-
 Homo sapiens
-
2.4.2.4 esophagus tumor Homo sapiens
-
2.4.2.4 lung cancer cell
-
 Homo sapiens
-
2.4.2.4 MCF-7 cell
-
 Homo sapiens
-
2.4.2.4 ovarian cancer cell malignant tissue Homo sapiens
-
2.4.2.4 pancreatic cancer cell
-
 Homo sapiens
-
2.4.2.4 stomach tumor tissue Homo sapiens
-
2.4.2.4 urinary bladder cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.4 5-fluoro-2'-deoxyuridine + phosphate
-
 Homo sapiens 5-fluorouracil + 2-deoxyribose-1-phosphate
-
 ?
2.4.2.4 deoxyuridine + phosphate
-
 Homo sapiens uracil + 2-deoxy-D-ribose 1-phosphate
-
 r
2.4.2.4 additional information formation of blood/brain barrier and repair following brain injury Homo sapiens ?
-
 ?
2.4.2.4 additional information angiogenic activity Homo sapiens ?
-
 ?
2.4.2.4 thymidine + phosphate
-
 Homo sapiens thymine + 2-deoxy-D-ribose 1-phosphate
-
 r