EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.2.3 | 2',3'-Dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 2'-deoxylyxofuranosyl-5-ethyluracil | - |
Rattus norvegicus | |
2.4.2.3 | 2,2'-Anhydro-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 2,3'-Anhydro-2'-deoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 2,5'-Anhydro-2'-deoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 3'-Azido-2',3'-dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 3'-Azido-2',3'-dideoxy-5-methyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 3'-Bromo-2',3'-dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 3'-Chloro-2',3'-dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 3'-Chloro-2',3'-dideoxy-5-methyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 3'-O-Acetyl-2,2'-anhydro-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | Arabinofuranosyl-5-ethyluracil | - |
Rattus norvegicus | |
2.4.2.4 | 2',3'-Dideoxy-5-ethyluridine | 9% inhibition at 10 mM | Rattus norvegicus | |
2.4.2.4 | 3'-Azido-2',3'-dideoxy-5-ethyluridine | 16% inhibition at 10 mM | Rattus norvegicus | |
2.4.2.4 | 3'-Azido-2',3'-dideoxy-5-methyluridine | 6% inhibition at 10 mM | Rattus norvegicus | |
2.4.2.4 | 3'-Bromo-2',3'-dideoxy-5-ethyluridine | 9% inhibition at 5 mM | Rattus norvegicus | |
2.4.2.4 | 3'-Chloro-2',3'-dideoxy-5-ethyluridine | 26% inhibition at 10 mM | Rattus norvegicus | |
2.4.2.4 | 3'-Chloro-2',3'-dideoxy-5-methyluridine | 18% inhibition at 10 mM | Rattus norvegicus | |
2.4.2.4 | Arabinofuranosyl-5-ethyluracil | 10% inhibition at 10 mM | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.3 | Rattus norvegicus | - |
- |
- |
2.4.2.4 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.2.3 | intestinal mucosa | - |
Rattus norvegicus | - |
2.4.2.4 | intestinal mucosa | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.3 | arabinofuranosyl-5-ethyluracil + phosphate | weak substrate | Rattus norvegicus | 5-ethyluracil + arabinose-1-phosphate | - |
? | |
2.4.2.3 | additional information | no substrates: 3'-azido-2',3'-dideoxy-5-methyluridine, 3'-azido-2',3'-dideoxy-5-ethyluridine, 2',3'-dideoxy-5-ethyluridine, 3'-chloro-2',3'-dideoxy-5-ethyluridine, 3'-chloro-2',3'-dideoxy-5-methyluridine, 3'-bromo-2',3'-dideoxy-5-ethyluridine, 2'-deoxylyxofuranosyl-5-ethyluracil, 3'-O-acetyl-2,2'-anhydro-5-ethyluridine, 2,3'-anhydro-2'-deoxy-5-ethyluridine, 2,5'-anhydro-2'-deoxy-5-ethyluridine | Rattus norvegicus | ? | - |
? | |
2.4.2.4 | thymidine + phosphate | - |
Rattus norvegicus | thymine + 2-deoxy-D-ribose 1-phosphate | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.2.3 | 0.056 | - |
3'-Azido-2',3'-dideoxy-5-methyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 0.107 | - |
Arabinofuranosyl-5-ethyluracil | - |
Rattus norvegicus | |
2.4.2.3 | 0.109 | - |
2',3'-Dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 0.21 | - |
3'-Chloro-2',3'-dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 0.225 | - |
3'-Azido-2',3'-dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 0.361 | - |
3'-Chloro-2',3'-dideoxy-5-methyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 0.448 | - |
3'-Bromo-2',3'-dideoxy-5-ethyluridine | - |
Rattus norvegicus | |
2.4.2.3 | 1.003 | - |
2'-deoxylyxofuranosyl-5-ethyluracil | - |
Rattus norvegicus |