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Literature summary extracted from

  • Bailly, P.; Piller, F.; Cartron, J.P.
    Characterization and specific assay for a galactoside beta-3-galactosyltransferase of human kidney (1988), Eur. J. Biochem., 173, 417-422.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.1.179 glycerol requirement, above 20% w/v Homo sapiens

General Stability

EC Number General Stability Organism
2.4.1.179 glycerol, 20% w/v and above, stabilizes Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.179 additional information inhibition by salt-concentrations above 0.1 M; no inhibition by N-acetylgalactosamine Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.179 0.17
-
 UDP-galactose
-
 Homo sapiens
2.4.1.179 2.5
-
 lactosylceramide
-
 Homo sapiens
2.4.1.179 242
-
 lactose
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.179 membrane
-
 Homo sapiens 16020
-
2.4.1.179 microsome
-
 Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.179 Cd2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-glycolipid Homo sapiens involved in elongation of oligosaccharide chains in glycolipids UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-glycolipid
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.179 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.179 kidney
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.179 UDP-galactose + asialo-fetuin
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-asialo-fetuin
-
 ?
2.4.1.179 UDP-galactose + asialo-glycophorin A
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-asialo-glycophorin A
-
 ?
2.4.1.179 UDP-galactose + asialo-orosomucoid
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-asialo-orosomucoid
-
 ?
2.4.1.179 UDP-galactose + beta-D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-beta-D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
2.4.1.179 UDP-galactose + beta-D-galactosyl-O-4-nitrophenyl
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-beta-D-galactose-O-4-nitrophenyl
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucose i.e. lactose Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucose
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-glycolipid involved in elongation of oligosaccharide chains in glycolipids Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-glycolipid
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R substrate specificity Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R hydrophobic substrates preferred Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R poor substrates are alpha-galactosides Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R R may be an oligosaccharide or a glycolipid Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R
-
 ?
2.4.1.179 UDP-galactose + D-galactosyl-1,4-beta-D-glucosyl-R p-nitrophenyl-beta-glycosides of galactose or lactose are by far the best substrates among oligosaccharides Homo sapiens UDP + D-galactosyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyl-R
-
 ?
2.4.1.179 UDP-galactose + ganglioside GM2
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-ganglioside GM2
-
 ?
2.4.1.179 UDP-galactose + lactosylceramide best glycolipid substrate Homo sapiens ?
-
 ?
2.4.1.179 UDP-galactose + methyl-beta-galactoside
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-methyl-beta-galactoside
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.179 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.179 6
-
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.179 5.3 7.5 about 80% of maximal activity at pH 5.3 and about 55% of maximal activity at pH 7.5 Homo sapiens