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Literature summary extracted from

  • Ju, T.; Brewer, K.; D'Souza, A.; Cummings, R.D.; Canfield, W.M.
    Cloning and expression of human core 1 beta1,3-galactosyltransferase (2002), J. Biol. Chem., 277, 178-186.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.122 DNA and amino acid sequence determination Mus musculus
2.4.1.122 DNA and amino acid sequence determination Rattus norvegicus
2.4.1.122 DNA and amino acid sequence determination Caenorhabditis elegans
2.4.1.122 DNA and amino acid sequence determination and analysis, transient functional expression in human 293T cells as wild-type and soluble, i.e. secreted into the medium, epitope-tagged protein, stable functional expression of the soluble epitope-tagged enzyme in CHO-K1 and Lec1-CHO cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.122 additional information type II transmembrane protein Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.122 Caenorhabditis elegans Q18515
-
-
2.4.1.122 Homo sapiens Q9NS00
-
-
2.4.1.122 Mus musculus Q9JJ06
-
-
2.4.1.122 Rattus norvegicus Q9JJ05
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.122 partial, recombinant soluble epitope-tagged enzyme from 293T cell medium Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.122 brain
-
 Homo sapiens
-
2.4.1.122 colon low content Homo sapiens
-
2.4.1.122 heart high content Homo sapiens
-
2.4.1.122 kidney high content Homo sapiens
-
2.4.1.122 leukocyte
-
 Homo sapiens
-
2.4.1.122 liver high content Homo sapiens
-
2.4.1.122 lung
-
 Homo sapiens
-
2.4.1.122 placenta high content Homo sapiens
-
2.4.1.122 skeletal muscle
-
 Homo sapiens
-
2.4.1.122 small intestine low content Homo sapiens
-
2.4.1.122 spleen low content Homo sapiens
-
2.4.1.122 thymus low content Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.122 UDP-galactose + glycoprotein N-acetyl-D-galactosamine threonine alpha-D-galactosamine is preferred to serine alpha-D-galactosamine Homo sapiens UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
2.4.1.122 UDP-galactose + glycoprotein N-acetyl-D-galactosamine high specificity for N-acetylgalactosaminyl residues linked to serine or threonine Homo sapiens UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
2.4.1.122 UDP-galactose + N-acetyl-alpha-D-galactosaminyl-phenyl
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-phenyl
-
 ?