Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Brockhausen, I.; Romero, P.A.; Herscovics, A.
    Glycosyltransferase changes upon differentiation of CaCo-2 human colonic adenocarcinoma cells (1991), Cancer Res., 51, 3136-3142.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.102 0.36
-
 beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-benzyl undifferentiated CaCo-2, colonic adenocarcinoma, cells Homo sapiens
2.4.1.102 0.43
-
 beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-benzyl CaCo-2, colonic adenocarcinoma, cells differentiated to enterocytes Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.102 Homo sapiens
-
-
-
2.4.1.146 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.102 Caco-2 cell
-
 Homo sapiens
-
2.4.1.102 colonic adenocarcinoma cell
-
 Homo sapiens
-
2.4.1.146 Caco-2 cell
-
 Homo sapiens
-
2.4.1.146 colonic adenocarcinoma cell
-
 Homo sapiens
-
2.4.1.146 enterocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.102 0.00015
-
 undifferentiated CaCo-2, colonic adenocarcinoma, cells Homo sapiens
2.4.1.102 0.00034
-
 CaCo-2, colonic adenocarcinoma, cells differentiated to enterocytes Homo sapiens
2.4.1.146 0.0000007
-
 CaCo-2, colonic adenocarcinoma, cells differentiated to enterocytes Homo sapiens
2.4.1.146 0.0000015
-
 undifferentiated CaCo-2, colonic adenocarcinoma, cells Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.102 UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-benzyl
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-benzyl
-
 ?
2.4.1.102 UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R
-
 Homo sapiens UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
-
 ?
2.4.1.146 UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-benzyl
-
 Homo sapiens UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-benzyl
-
 ?
2.4.1.146 UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
-
 Homo sapiens UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R
-
 ?