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Literature summary extracted from

  • Gottfries, J.; Percy, A.K.; Mansson, J.E.; Fredman, P.; Wikstrand, C.J.; Friedman, H.S.; Bigner, D.D.; Svennerholm, L.
    Glycolipids and glycosyltransferases in permanent cell lines established from human medulloblastomas (1991), Biochim. Biophys. Acta, 1081, 253-261.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.206 Golgi apparatus
-
 Homo sapiens 5794
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.206 UDP-N-acetyl-D-glucosamine + lactosylceramide Homo sapiens ganglioside metabolism and pattern UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?
2.4.1.206 UDP-N-acetyl-D-glucosamine + lactosylceramide Homo sapiens biosynthetic pathway of lactoseries and ganglioseries UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.206 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.206 brain
-
 Homo sapiens
-
2.4.1.206 medulloblastoma cell line Daoy and D341 Med, cultured both in vitro and as xenografts in nude mice Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.206 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.206 UDP-N-acetyl-D-glucosamine + D-galactosyl-1,4-beta-D-glucosylceramide i.e. lactosylceramide Homo sapiens UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?
2.4.1.206 UDP-N-acetyl-D-glucosamine + lactosylceramide ganglioside metabolism and pattern Homo sapiens UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?
2.4.1.206 UDP-N-acetyl-D-glucosamine + lactosylceramide biosynthetic pathway of lactoseries and ganglioseries Homo sapiens UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.206 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.206 7.3
-
 assay at Homo sapiens