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Literature summary extracted from

  • Lee, Y.B.; Joe, Y.A.; Wolff, E.C.; Dimitriadis, E.K.; Park, M.H.
    Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor (1999), Biochem. J., 340, 273-281.
No PubMed abstract available

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.46 Homo sapiens
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-
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.46 [eIF5A-precursor]-lysine + spermidine
-
 Homo sapiens [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine i.e. [eIF5A-precursor]-N6-(4-aminobutyl)lysine ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.5.1.46 NAD+ not dependent on NAD+ for binding of eIF5A Homo sapiens