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Literature summary extracted from

  • Hughes, K.T.; Dessen, A.; Gray, J.P.; Grubmeyer, C.
    The Salmonella typhimurium nadC gene: sequence determination by use of Mud-P22 and purification of quinolinate phosphoribosyltransferase (1993), J. Bacteriol., 175, 479-486.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.2.19 subcloned into a T7-based expression system Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.19 0.0196
-
 quinolinate
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.4.2.19 0.02
-
 quinolinate
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.4.2.19 0.032
-
 5-phospho-alpha-D-ribose 1-diphosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.4.2.19 0.0322
-
 5-phospho-alpha-D-ribose 1-diphosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.2.19 35000
-
 2 * 35000, SDS-PAGE Salmonella enterica subsp. enterica serovar Typhimurium
2.4.2.19 72000
-
 gel filtration Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.19 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.19
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.2.19 0.9
-
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.19 pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium nicotinate D-ribonucleotide + diphosphate + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.2.19 dimer 2 * 35000, SDS-PAGE Salmonella enterica subsp. enterica serovar Typhimurium