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Literature summary extracted from

  • Roberts, E.
    Studies of transamination (1954), Arch. Biochem. Biophys., 48, 395-401.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.8 streptomycin weak, with 2,4-diaminoglutarate as substrate Escherichia coli
2.6.1.8 streptomycin weak, with 2,4-diaminoglutarate as substrate Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.8 L-2,5-diaminopentanoate + 2-oxoglutarate Escherichia coli
-
 5-amino-2-oxopentanoate + L-glutamate
-
 ?
2.6.1.8 L-2,5-diaminopentanoate + 2-oxoglutarate Aspergillus fumigatus
-
 5-amino-2-oxopentanoate + L-glutamate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.8 Aspergillus fumigatus
-
-
-
2.6.1.8 Escherichia coli
-
-
-
2.6.1.8 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.8 partial Mus musculus
2.6.1.8 partial Escherichia coli
2.6.1.8 partial Aspergillus fumigatus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.8 brain
-
 Mus musculus
-
2.6.1.8 liver
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.8 2,4-diaminoglutarate + 2-oxoglutarate
-
 Mus musculus 4-amino-2-oxobutanoate + L-glutamate
-
 ?
2.6.1.8 2,4-diaminoglutarate + 2-oxoglutarate
-
 Escherichia coli 4-amino-2-oxobutanoate + L-glutamate
-
 ?
2.6.1.8 2,4-diaminoglutarate + 2-oxoglutarate
-
 Aspergillus fumigatus 4-amino-2-oxobutanoate + L-glutamate
-
 ?
2.6.1.8 L-2,5-diaminopentanoate + 2-oxoglutarate
-
 Escherichia coli 5-amino-2-oxopentanoate + L-glutamate
-
 ?
2.6.1.8 L-2,5-diaminopentanoate + 2-oxoglutarate
-
 Aspergillus fumigatus 5-amino-2-oxopentanoate + L-glutamate
-
 ?
2.6.1.8 additional information omega-amino monocarboxylic acids, e.g. 5-aminopentanoate 4-aminobutanoate, L-aspartate may be transaminated with 2-oxoglutarate by crude enzyme extracts Mus musculus ?
-
 ?
2.6.1.8 additional information omega-amino monocarboxylic acids, e.g. 5-aminopentanoate 4-aminobutanoate, L-aspartate may be transaminated with 2-oxoglutarate by crude enzyme extracts Escherichia coli ?
-
 ?
2.6.1.8 additional information omega-amino monocarboxylic acids, e.g. 5-aminopentanoate 4-aminobutanoate, L-aspartate may be transaminated with 2-oxoglutarate by crude enzyme extracts Aspergillus fumigatus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.8 30
-
 assay at Mus musculus
2.6.1.8 30
-
 assay at Escherichia coli
2.6.1.8 30
-
 assay at Aspergillus fumigatus

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.8 pyridoxal 5'-phosphate
-
 Escherichia coli