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Literature summary extracted from

  • Yip, M.C.M.
    The enzymic synthesis of disialoganglioside: rat brain cytidine-5-monophospho-N-acetylneuraminic acid: monosialoganglioside (GM1) sialyltransferase (1973), Biochim. Biophys. Acta, 306, 298-306.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.4.3.2 Triton CF-54 activation Rattus norvegicus
2.4.3.2 Triton CF-54 activates, can partially be replaced by cutscum or Triton X-100, not by sodium taurocholate or deoxycholate, Tween 80 or cholic acid Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.3.2 CMP-N-acetylneuraminate above 0.2 M Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.3.2 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.2 Rattus norvegicus
-
 Sprague-Dawley strain
-
2.4.3.2 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley strain
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.3.2 brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Rattus norvegicus CMP + ganglioside GD1a i.e. ganglioside GD1a ?
2.4.3.2 CMP-N-acetyl-beta-neuraminate + ganglioside GM1a
-
 Rattus norvegicus Sprague-Dawley CMP + ganglioside GD1a i.e. ganglioside GD1a ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.3.2 6.5
-
 cacodylate buffer Rattus norvegicus