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Literature summary extracted from

  • Götting, C.; Kuhn, J.; Tinneberg, H.R.; Brinkmann, T.; Kleesiek, K.
    High xylosyltransferase activities in human follicular fluid and cultured granulosa-lutein cells (2002), Mol. Hum. Reprod., 8, 1079-1086.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.26 Glycosaminoglycans associate with the enzyme Homo sapiens
2.4.2.26 heparin
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.2.26 extracellular in cell culture supernatant Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine Homo sapiens enzyme may play a role in maintaining the haemostatic potential of the follicular fluid UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine Homo sapiens enzyme is associated with large chondroitin sulfate-containing proteoglycans UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine Homo sapiens enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.26 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.26 from cell culture supernatant Homo sapiens
2.4.2.26 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.26 EFO-27 cell low activity Homo sapiens
-
2.4.2.26 granulosa cell cell culture Homo sapiens
-
2.4.2.26 HeLa cell low activity Homo sapiens
-
2.4.2.26 JAR cell
-
 Homo sapiens
-
2.4.2.26 additional information no activity in EFO-21 cells Homo sapiens
-
2.4.2.26 ovarian follicle mainly produced by granulosa-lutein cells Homo sapiens
-
2.4.2.26 ovarian follicle follicular fluid Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.2.26 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine enzyme may play a role in maintaining the haemostatic potential of the follicular fluid Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine enzyme is associated with large chondroitin sulfate-containing proteoglycans Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine enzyme initiates the biosynthesis of glycosaminoglycan lateral chains in proteoglycans by transfer of xylose from UDP-xylose to specific serine residues of the core protein Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-D-xylose + bikunin recombinant mutant bikunin Homo sapiens UDP + D-xylosyl-bikunin bound to serine residue ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.2.26 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.2.26 6.5
-
 assay at Homo sapiens