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Literature summary extracted from

  • Götting, C.; Kuhn, J.; Brinkmann, T.; Kleesiek, K.
    Xylosylation of alternatively spliced isoforms of Alzheimer APP by xylosyltransferase (1998), J. Protein Chem., 17, 295-302.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.26 0.0006
-
 bikunin recombinant mutant bikunin Homo sapiens
2.4.2.26 0.019
-
 SENEGSGMAEQK
-
 Homo sapiens
2.4.2.26 0.019
-
 SENEGSGMAQQK
-
 Homo sapiens
2.4.2.26 0.02
-
 TENEGSGLTNIK
-
 Homo sapiens
2.4.2.26 0.022
-
 bikunin-derived aminoterminus homologous peptide
-
 Homo sapiens
2.4.2.26 0.022
-
 QEEEGSGGGQK
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.2.26 cytosol
-
 Homo sapiens 5829
-
2.4.2.26 extracellular human cell cultures Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.26 Homo sapiens
-
-
-
2.4.2.26 Rattus norvegicus
-
 Lewis1WR1
-
2.4.2.26 Rattus norvegicus Lewis1WR1
-
 Lewis1WR1
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.26 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.26 brain
-
 Homo sapiens
-
2.4.2.26 brain
-
 Rattus norvegicus
-
2.4.2.26 cartilage
-
 Rattus norvegicus
-
2.4.2.26 cartilage sternal, from heart Homo sapiens
-
2.4.2.26 cerebrospinal fluid
-
 Homo sapiens
-
2.4.2.26 chondrocyte from heart sternal cartilage Homo sapiens
-
2.4.2.26 chondrocyte cell culture supernatant Homo sapiens
-
2.4.2.26 heart
-
 Rattus norvegicus
-
2.4.2.26 heart sternal cartilage Homo sapiens
-
2.4.2.26 JAR cell
-
 Homo sapiens
-
2.4.2.26 kidney
-
 Homo sapiens
-
2.4.2.26 kidney
-
 Rattus norvegicus
-
2.4.2.26 lung
-
 Homo sapiens
-
2.4.2.26 lung
-
 Rattus norvegicus
-
2.4.2.26 additional information activity in several human cell lines, culture supernatant, overview Homo sapiens
-
2.4.2.26 ovary low activity Rattus norvegicus
-
2.4.2.26 serum
-
 Homo sapiens
-
2.4.2.26 serum from heart blood Rattus norvegicus
-
2.4.2.26 spleen
-
 Rattus norvegicus
-
2.4.2.26 testis
-
 Rattus norvegicus
-
2.4.2.26 thyroid gland
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.2.26 additional information
-
 activity in several tissues, overview Rattus norvegicus
2.4.2.26 additional information
-
 activity in several human cell lines, overview Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate Rattus norvegicus UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence Homo sapiens UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence Rattus norvegicus UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate Rattus norvegicus Lewis1WR1 UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-alpha-D-xylose + [protein]-L-serine transfers a beta-D-xylosyl residue to specific serine residues dependent on the consensus signal sequence Rattus norvegicus Lewis1WR1 UDP + [protein]-3-O-(beta-D-xylosyl)-L-serine
-
 ?
2.4.2.26 UDP-D-xylose + bikunin recombinant mutant bikunin Rattus norvegicus UDP + D-xylosyl-bikunin
-
 ?
2.4.2.26 UDP-D-xylose + bikunin recombinant mutant bikunin Homo sapiens UDP + D-xylosyl-bikunin bound to serine residue ?
2.4.2.26 UDP-D-xylose + bikunin recombinant mutant bikunin Rattus norvegicus Lewis1WR1 UDP + D-xylosyl-bikunin
-
 ?
2.4.2.26 UDP-D-xylose + bikunin-derived aminoterminus homologous peptide
-
 Homo sapiens UDP + xylosyl-serine bikunin-derived aminoterminus homologous peptide
-
 ?
2.4.2.26 UDP-D-xylose + QEEEGSGGGQK
-
 Homo sapiens UDP + ?
-
 ?
2.4.2.26 UDP-D-xylose + SENEGSGMAEQK synthetic leukocyte-derived amyloid precursor-like protein homologous peptide Homo sapiens UDP + SENEGS(-D-xylose)GMAEQK
-
 ?
2.4.2.26 UDP-D-xylose + SENEGSGMAQQK
-
 Homo sapiens UDP + ?
-
 ?
2.4.2.26 UDP-D-xylose + TENEGSGLTNIK synthetic leukocyte-derived beta-A4-amyloid protein precursor homologous peptide Homo sapiens UDP + TENEGS(-D-xylose)GLTNIK
-
 ?
2.4.2.26 UDP-D-xylose + TENEGSGLTNIK
-
 Homo sapiens UDP + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.2.26 XT
-
 Homo sapiens
2.4.2.26 XT
-
 Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.2.26 37
-
 assay at Homo sapiens
2.4.2.26 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.2.26 6.5
-
 assay at Homo sapiens
2.4.2.26 6.5
-
 assay at Rattus norvegicus