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Literature summary extracted from

  • White, M.W.; Vandenbark, A.A.; Barney, C.L.; Ferro, A.J.
    Structural analogs of 5'-methylthioadenosine as substrates and inhibitors of 5'-methylthioadenosine phosphorylase and as inhibitors of human lymphocyte transformation (1982), Biochem. Pharmacol., 31, 503-507.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.28 5'-deoxy-5'-methylthiotubercidin
-
 Homo sapiens
2.4.2.28 5'-methylthiotubercidin
-
 Homo sapiens
2.4.2.28 adenine
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.2.28 0.023
-
 5'-deoxyadenosine
-
 Homo sapiens
2.4.2.28 0.026
-
 5'-deoxy-5'-methylthioadenosine
-
 Homo sapiens
2.4.2.28 7.5
-
 phosphate
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.28 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.28 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.28 lymphocyte peripheral blood Homo sapiens
-
2.4.2.28 peripheral blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.28 5'-deoxy-5'-methylthioadenosine + phosphate
-
 Homo sapiens adenine + 5-methylthio-D-ribose 1-phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.2.28 47
-
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.2.28 0.031
-
 5'-methylthiotubercidin
-
 Homo sapiens
2.4.2.28 0.172
-
 adenine
-
 Homo sapiens