Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Koszalka, G.W.; Krenitsky, T.A.
    5'-Methyladenosine (MTA) phosphorylase from promastigotes of Leishmania donovani (1986), Adv. Exp. Med. Biol., 195B, 559-563.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.2.28 2'-deoxyguanosine
-
 Leishmania donovani
2.4.2.28 2'-deoxyinosine weak, competitive Leishmania donovani
2.4.2.28 adenine arabinoside weak, competitive Leishmania donovani
2.4.2.28 guanosine weak, competitive Leishmania donovani
2.4.2.28 Inosine weak, competitive Leishmania donovani

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.2.28 89000
-
 gel filtration Leishmania donovani

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.2.28 adenosine + phosphate Leishmania donovani
-
 adenine + D-ribose 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.2.28 Leishmania donovani
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.2.28
-
 Leishmania donovani

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.2.28 promastigote
-
 Leishmania donovani
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.2.28 2'-deoxyadenosine + phosphate
-
 Leishmania donovani adenine + 2-deoxy-D-ribose 1-phosphate
-
 ?
2.4.2.28 5'-deoxyadenosine + phosphate
-
 Leishmania donovani adenine + 5-deoxy-D-ribose 1-phosphate
-
 ?
2.4.2.28 5'-methylthioadenosine + phosphate 5'-methylthioadenosine is the best substrate Leishmania donovani adenine + 5-methylthio-D-ribose 1-phosphate
-
 r
2.4.2.28 5'-methylthioadenosine + phosphate preferred direction of reaction is temperature-dependent Leishmania donovani adenine + 5-methylthio-D-ribose 1-phosphate
-
 r
2.4.2.28 adenosine + phosphate
-
 Leishmania donovani adenine + D-ribose 1-phosphate
-
 ?
2.4.2.28 adenosine + phosphate
-
 Leishmania donovani adenine + D-ribose 1-phosphate
-
 r
2.4.2.28 additional information substrate specificity Leishmania donovani ?
-
 ?

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.4.2.28 20 60
-
 Leishmania donovani