Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Tudball, N.; Thomas, J.H.
    L-Serine O-sulphate-degrading system of rat liver (1971), Methods Enzymol., 17B, 361-367.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.3.1.10 Co2+
-
 Rattus norvegicus
4.3.1.10 D-serine O-sulfate
-
 Rattus norvegicus
4.3.1.10 DL-homoserine O-sulfate weak competitive Rattus norvegicus
4.3.1.10 Fe2+
-
 Rattus norvegicus
4.3.1.10 Hg2+
-
 Rattus norvegicus
4.3.1.10 hydroxylamine
-
 Rattus norvegicus
4.3.1.10 iodoacetic acid
-
 Rattus norvegicus
4.3.1.10 O-acetyl-L-serine potent non-competitive Rattus norvegicus
4.3.1.10 O-phospho-L-serine potent non-competitive Rattus norvegicus
4.3.1.10 p-chloromercuribenzoate at a concentration of 0.1 mM, partly reversible with 2-mercaptoethanol Rattus norvegicus
4.3.1.10 Pb2+
-
 Rattus norvegicus
4.3.1.10 Zn2+
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.3.1.10 23
-
 L-serine O-sulfate
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.10 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.3.1.10
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.3.1.10 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.3.1.10 1.48
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
4.3.1.10 -20°C, stable for several weeks Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.10 beta-chloroalanine
-
 Rattus norvegicus ?
-
 ?
4.3.1.10 D-serine-O-sulfate activity: 1/40 that towards L-isomer Rattus norvegicus pyruvate + NH3 + SO42-
-
 ?
4.3.1.10 L-serine O-sulfate
-
 Rattus norvegicus pyruvate + NH3 + sulfate
-
 ?
4.3.1.10 L-seryl-glycine O-sulfate not very efficient substrate Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-alanine O-sulfate not very efficient substrate Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-leucine O-sulfate not very efficient substrate Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-phenylalanine O-sulfate not very efficient substrate Rattus norvegicus ?
-
 ?
4.3.1.10 L-seryl-L-valine O-sulfate not very efficient substrate Rattus norvegicus ?
-
 ?
4.3.1.10 L-threonine O-sulfate weak activity Rattus norvegicus 2-oxobutanoate + NH3 + SO42-
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.3.1.10 38
-
 enzyme assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.3.1.10 7
-
 in 0.1 M Tris-HCl Rattus norvegicus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
4.3.1.10 4.5 8 stable between Rattus norvegicus