Literature summary extracted from

Moore, J.D.; Hawkins, A.R.; Charles, I.G.; Deka, R.; Coggins, J.R.; Cooper, A.; Kelly, S.M.; Price, N.C.
Characterization of the type I dehydroquinase from Salmonella typhi (1993), Biochem. J., 295, 277-285.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.2.1.10	overexpression in Escherichia coli	Salmonella enterica subsp. enterica serovar Typhi

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.2.1.10	diethyl dicarbonate	-	Salmonella enterica subsp. enterica serovar Typhi
4.2.1.10	guanidine hydrochloride	-	Salmonella enterica subsp. enterica serovar Typhi
4.2.1.10	NaBH4	irreversible inactivation in presence of 3-dehydroquinate	Salmonella enterica subsp. enterica serovar Typhi

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
4.2.1.10	0.018	-	3-dehydroquinate	-	Salmonella enterica subsp. enterica serovar Typhi

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
4.2.1.10	27700	-	2 * 27700	Salmonella enterica subsp. enterica serovar Typhi
4.2.1.10	61500	-	gel filtration	Salmonella enterica subsp. enterica serovar Typhi

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.1.10	Salmonella enterica subsp. enterica serovar Typhi	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
4.2.1.10	-	Salmonella enterica subsp. enterica serovar Typhi

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
4.2.1.10	229	-	-	Salmonella enterica subsp. enterica serovar Typhi

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.1.10	3-dehydroquinate	-	Salmonella enterica subsp. enterica serovar Typhi	3-dehydroshikimate + H2O	-	?

Subunits

EC Number	Subunits	Comment	Organism
4.2.1.10	dimer	2 * 27700	Salmonella enterica subsp. enterica serovar Typhi

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Release 2023.1 (January 2023)