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Literature summary extracted from

  • Myers, P.A.; Zatman, L.J.
    The metabolism of trimethylamine N-oxide by Bacillus PM 6 (1971), Biochem. J., 121, 10P.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.2.32 glutathione strongly stimulates Bacillus sp. (in: Bacteria)
4.1.2.32 L-ascorbate strongly stimutates Bacillus sp. (in: Bacteria)

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.2.32 Proadifen hydrochloride i.e. SKF 525-A, , competitive Bacillus sp. (in: Bacteria)
4.1.2.32 trimethylamine non-competitive Bacillus sp. (in: Bacteria)

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.2.32 2.85
-
 Trimethylamine N-oxide
-
 Bacillus sp. (in: Bacteria)

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.2.32 Fe2+ strongly stimulates Bacillus sp. (in: Bacteria)

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.2.32 36000 47000 sedimentation equilibrium centrifugation Bacillus sp. (in: Bacteria)
4.1.2.32 50000
-
 gel filtration Bacillus sp. (in: Bacteria)

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.32 Bacillus sp. (in: Bacteria)
-
 PM 6
-
4.1.2.32 Bacillus sp. (in: Bacteria) PM 6
-
 PM 6
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.32 (+)-Propoxyphene N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) ?
-
 ?
4.1.2.32 (+)-Propoxyphene N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) PM 6 ?
-
 ?
4.1.2.32 Benzyldimethylamine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) ?
-
 ?
4.1.2.32 Benzyldimethylamine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) PM 6 ?
-
 ?
4.1.2.32 Chlorpromazine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) ?
-
 ?
4.1.2.32 Chlorpromazine N-oxide 5% of the activity with trimethylamine N-oxide Bacillus sp. (in: Bacteria) PM 6 ?
-
 ?
4.1.2.32 Trimethylamine N-oxide anaerobic conditions Bacillus sp. (in: Bacteria) Dimethylamine + formaldehyde
-
 ?
4.1.2.32 Trimethylamine N-oxide anaerobic conditions Bacillus sp. (in: Bacteria) PM 6 Dimethylamine + formaldehyde
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.2.32 monomer 1* 37000, SDS-PAGE Bacillus sp. (in: Bacteria)

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.2.32 7.5
-
-
 Bacillus sp. (in: Bacteria)